Increasing sample sizes do not always increase the power of UMPU-tests for 2×2 tables

Abstract.

We consider the uniformly most powerful unbiased (UMPU) one-sided test for the comparison of two proportions based on sample sizes m and n, i.e., the randomized version of Fisher's exact one-sided test. It will be shown that the power function of the one-sided UMPU-test based on sample sizes m and n can coincide with the power function of the UMPU-test based on sample sizes m+1 and n for certain levels on the entire parameter space. A characterization of all such cases with identical power functions is derived. Finally, this characterization is closely related to number theoretical problems concerning Fermat-like binomial equations. Some consequences for Fisher's original exact test will be discussed, too.