Zusammenfassung
Die Besprechung dermatologischer Systemtherapien führt nicht nur im onkologischen Bereich regelmäßig zur Frage nach deren Auswirkungen auf die männliche Fertilität. Gerade bei neueren Medikamenten ist die Datenlage zu gonadotoxischen und anderen fertilitätsrelevanten Aspekten limitiert. Darüber hinaus bestehen individuelle Suszeptibilitätsunterschiede und eine Abhängigkeit von andrologischen Vorerkrankungen. Zur Fertilitätsprotektion kommt neben der Auswahl fertilitätsschonender Medikamente eine Spermienkryokonservierung in Betracht.
Abstract
Dermatologists administer a broad spectrum of systemic medications. However, our current knowledge of potential risks to male fertility is still limited, particularly with the new emerging therapies in dermato-oncology. Individual differences in susceptibility and a history of andrological disorders influence prognostic values. For fertility protection, a thoughtful selection of medication and/or sperm cryopreservation remain the best options.
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S. Grunewald und U. Paasch geben an, dass kein Interessenkonflikt besteht.
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Grunewald, S., Paasch, U. Medikamentöse Therapie dermatologischer Erkrankungen. Hautarzt 66, 913–918 (2015). https://doi.org/10.1007/s00105-015-3706-x
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DOI: https://doi.org/10.1007/s00105-015-3706-x