Skip to main content
Log in

Komplexe Becken- und Sarkomchirurgie mit Gefäßersatz

Complex pelvic and sarcoma surgery with vascular replacement

  • Leitthema
  • Published:
Der Chirurg Aims and scope Submit manuscript

Zusammenfassung

Durch die Optimierung der onko- und gefäßchirurgischen Operationstechnik, modernste anästhesiologische und intensivtherapeutische Verfahren sowie effektivere multimodale Therapien ist eine zunehmende Erweiterung der Indikationsstellungen für komplexe Resektionen bei Patienten mit lokal weit fortgeschrittenen malignen Tumoren und damit die Aussicht auf Heilung möglich geworden. Ausgedehnte Malignome mit Infiltration von Gefäßen vitaler Relevanz oder solchen, die für den Extremitätenerhalt unabdingbar sind, bzw. maligne Tumoren dieser Gefäße selbst stellen jedoch aus mehreren Gründen eine erhebliche Herausforderung für die Expertise des Chirurgen und einen signifikanten Morbiditätsfaktor für die Patienten dar. Die Indikationsstellung sollte immer im gesamtonkologischen Kontext erfolgen. Bei der Operationsplanung und -durchführung sowie im postoperativen Verlauf ist deshalb große chirurgische und interdisziplinäre Erfahrung, insbesondere auch beim Management etwaiger Komplikationen essenziell. Im Folgenden sollen daher wichtige Aspekte der Indikationsstellung und Operationsdurchführung, onkologische Ergebnisse sowie Daten zur Morbidität und Mortalität bei relevanten Tumorentitäten des Retroperitoneums und des kleinen Beckens dargestellt und anhand von Beispielen erläutert werden.

Abstract

Due to optimization of surgical techniques in surgical oncology and vascular surgery, the most modern approaches of anesthesia and intensive care medicine and effective multimodal therapeutic strategies, locally advanced malignant tumors are resected more frequently with a potentially curative intent. In the case of extensive tumors with infiltration of vital vascular structures or of structures which are crucial for extremity preservation, the necessary surgical procedure for complete tumor removal poses a major challenge for the surgeon and incorporates a high risk of perioperative morbidity for the patient. The decision to attempt tumor resection should therefore always be based on a concept considering all aspects of the malignant disease. The treating team should be highly experienced in this complex field of surgery, not only with respect to the surgical approach but also regarding the management of postoperative complications. In this article relevant aspects of decision making, surgical technique and postoperative outcome for malignant tumors involving vascular structures of the retroperitoneum and pelvis are presented.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6
Abb. 7
Abb. 8
Abb. 9

Literatur

  1. Fatima J et al (2013) Primary angiosarcoma of the aorta, great vessels, and the heart. J Vasc Surg 57(3):756–764

    Article  PubMed  Google Scholar 

  2. Shuster TA et al (2002) Abdominal aortic sarcoma: report of a case with long-term survival and review of the literature. Ann Vasc Surg 16(5):545–549

    Article  PubMed  Google Scholar 

  3. Wachtel H et al (2015) Outcomes after resection of leiomyosarcomas of the inferior vena cava: a pooled data analysis of 377 cases. Surg Oncol 24(1):21–27

    Article  PubMed  Google Scholar 

  4. Wachtel H et al (2015) Resection of primary leiomyosarcoma of the inferior vena cava (IVC) with reconstruction: a case series and review of the literature. J Surg Oncol 111(3):328–333

    Article  PubMed  Google Scholar 

  5. Dull BZ et al (2013) Surgical management of retroperitoneal leiomyosarcoma arising from the inferior vena cava. J Gastrointest Surg 17(12):2166–2171

    Article  PubMed Central  PubMed  Google Scholar 

  6. Hollenbeck ST et al (2003) Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma. J Am Coll Surg 197(4):575–579

    Article  PubMed  Google Scholar 

  7. Lane WO et al (2015) Analysis of perioperative radiation therapy in the surgical treatment of primary and recurrent retroperitoneal sarcoma. J Surg Oncol 112(4):352–358

    Article  PubMed  Google Scholar 

  8. Kelly KJ et al (2015) Comparison of perioperative radiation therapy and surgery versus surgery alone in 204 patients with primary retroperitoneal sarcoma: a retrospective 2-institution study. Ann Surg 262(1):156–162

    Article  PubMed  Google Scholar 

  9. De Amorim Bernstein K, Delaney TF (2015) Role of radiation therapy for non-extremity soft tissue sarcomas. J Surg Oncol 111(5):604–614

    Article  PubMed  Google Scholar 

  10. Tan MC et al (2015) Histology-based classification predicts pattern of recurrence and improves risk stratification in primary retroperitoneal sarcoma. Ann Surg [Epub ahead of print]

  11. Bonvalot S et al (2009) Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control. J Clin Oncol 27(1):31–37

    Article  PubMed  Google Scholar 

  12. Gronchi A et al (2009) Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients. J Clin Oncol 27(1):24–30

    Article  PubMed  Google Scholar 

  13. Bonvalot S et al (2010) Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control. Ann Surg Oncol 17(6):1507–1514

    Article  PubMed  Google Scholar 

  14. Gronchi A, Pollock RE (2013) Quality of local treatment or biology of the tumor: which are the trump cards for loco-regional control of retroperitoneal sarcoma? Ann Surg Oncol 20(7):2111–2113

    Article  PubMed  Google Scholar 

  15. Gronchi A et al (2012) Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas. Ann Oncol 23(4):1067–1073

    Article  CAS  PubMed  Google Scholar 

  16. Miura JT et al (2015) Impact of chemotherapy on survival in surgically resected retroperitoneal sarcoma. Eur J Surg Oncol 41(10):1386–1392

    Article  CAS  PubMed  Google Scholar 

  17. Angele MK et al (2014) Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study. Ann Surg 260(5):749–754 (discussion 754–746)

    Article  PubMed Central  PubMed  Google Scholar 

  18. Schwarzbach MH et al (2006) Clinical results of surgery for retroperitoneal sarcoma with major blood vessel involvement. J Vasc Surg 44(1):46–55

    Article  PubMed  Google Scholar 

  19. Ohman JW et al (2013) Iliocaval and aortoiliac reconstruction following en bloc retroperitoneal leiomyosarcoma resection. J Vasc Surg 57(3):850

    Article  PubMed  Google Scholar 

  20. Brown KG et al (2015) Outcomes After En Bloc Iliac Vessel Excision and Reconstruction During Pelvic Exenteration. Dis Colon Rectum 58(9):850–856

    Article  PubMed  Google Scholar 

  21. Renzulli P et al (2009) Low-grade endometrial stromal sarcoma with inferior vena cava tumor thrombus and intracardiac extension: radical resection may improve recurrence free survival. Surg Oncol 18(1):57–64

    Article  PubMed  Google Scholar 

  22. Busuito BC et al (2012) Endometrial stromal sarcoma invading the abdominal aorta treated with aortic replacement. J Vasc Surg 55(3):844–846

    Article  PubMed  Google Scholar 

  23. Lentz SE et al (2014) Abdominal aortic resection and Y-graft placement to achieve complete cytoreduction in stage IIIc ovarian carcinoma. Obstet Gynecol 123(2 Pt 2 Suppl 2):486–488

    Article  PubMed  Google Scholar 

  24. Mehrabi A et al (2011) [Vascular replacement in abdominal tumor surgery]. Chirurg 82(10):887–897

    Article  CAS  PubMed  Google Scholar 

  25. Callegaro D et al (2015) Long-term morbidity after multivisceral resection for retroperitoneal sarcoma. Br J Surg 102(9):1079–1087

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. Pistorius.

Ethics declarations

Interessenkonflikt

S. Pistorius, C. Reeps und J. Weitz geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pistorius, S., Reeps, C. & Weitz, J. Komplexe Becken- und Sarkomchirurgie mit Gefäßersatz. Chirurg 87, 108–113 (2016). https://doi.org/10.1007/s00104-015-0123-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00104-015-0123-8

Schlüsselwörter

Keywords

Navigation