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Experimental models of colorectal cancer

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Diseases of the Colon & Rectum

Abstract

PURPOSE: A review ofin vivo andin vitro models of colorectal cancer is presented. METHODS: A retrospective literature review was performed with reference to CD-ROM Medline and Index Medicus. RESULTS: A comparison of the advantages and disadvantages of the models is presented in addition to a summary of individual model methodology and applications. CONCLUSIONS: Such models are a useful adjunct for surgical research in colorectal oncology.

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Authors and Affiliations

  1. From the Colorectal Unit, Department of Surgery, Royal Halifax Infirmary, University of Leeds Medical School, United Kingdom

    Anjan Banerjee M.Sc., M.S.(Lond.), D.M. (F.R.C.P., F.R.C.S.)

  2. Leeds General Infirmary and University of Leeds Medical School, Leeds, United Kingdom

    Philip Quirke B.M., Ph.D. (F.R.C.Path.)

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  1. Anjan Banerjee M.Sc., M.S.(Lond.), D.M.
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  2. Philip Quirke B.M., Ph.D.
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Mr. Banerjee is in receipt of support from the Yorkshire Cancer Research Organization.

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Banerjee, A., Quirke, P. Experimental models of colorectal cancer. Dis Colon Rectum 41, 490–505 (1998). https://doi.org/10.1007/BF02235764

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