Abstract
Fourteen volatile components including eight allypyrocatechol analgos were isolated and identified from the essential oil and ether soluble fraction of PhilippinePiper betle leaves (Piperaceae). The major constituents of PhilippinePiper betle oil were chavibetol and chavibetol acetate. Capillary GC analysis of the oil showed chavibetol (53.1%), chavibetol acetate (15.5%), caryophyllene (3.79%), allypyroacatechol diacetate (0.71%), campene (0.48%), chavibetol methyl ether (=methyl eugenol, 0.48%), eugenol (0.32%), α-pinene (0.21%), β-pinene (0.21%), α-limonene (0,14%), safrole (0.11%), 1,8-cineol (0.04%), and allylpyrocatechol monoacetate. The major component of the ether soluble fraction was allylpyrocatechol (2.38% of the leaves).
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Literature Cited
Krishnamurthi, A., Ed.-in-chief.:Wealth of India-Raw Materials. V. 8 CSIR, New Delhi, India, p 83 (1969).
Mercier, A.: The areca and the betle-Use of betle nut in the orient.Bull. Mens. Soc. Linn. Lyon.,13, 28 (1949).
Quisurnbing, E.:Medicinal Plants of the Philippiness. JMC Press, Inc., Quezon City, Philippines, (1978).
Evans, P.H., Bowers, W.S., and Funk, E.J.: Identification of fungicidal and nematocidal components in the leaves ofPiper betle.J. Agric. Food Chem.,32, 1254 (1984).
Bangar, G.P., Rao, R.E., and Varma, K.C.: Antimicrobial activity of leaves and oil ofPiper betle.Ind. J. Pharm. 28, 327 (1966).
Ali, S.M. and Mehta, R.K.: Preliminary pharmacological and anthelmintic studies of the essential oil ofPiper betle.Ind. J. Pharm. 32, 132 (1970).
Ueda, E. and Sasaki, T.: Chemical studies of Formosan plants I, Chemical constitutuents of the leaves ofPiper betle.Yakugaku Zasshi 71, 559 (1951).
Atal, C.K., Dhar, K.L., and Singh, J.: The chemistry of IndianPiper species.Lloydia 38, 256(1975).
Sharma, M.L., Kawat, A.K.S., Balasabrahmanyan, V.R., and Singh, A.: Studies on the essential oil of betle vine leaf (Piper betle).Indian Perfuner 27, 91(1983).
Budzikiewicz, H., Djerassi, C., and Williams, D.H.:Structure Elucidation of Natural Products by Mass Spectrometry, Holden-day Inc., San Francisco, USA, p 17 (1964).
Buckingham, J.:Dictionary of Organic Compounds, 5th ed., V.5, Chapman and Hall, New York, USA, p 4785 (1982).
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Rimando, A.M., Han, B.H., Park, J.H. et al. Studies on the constituents of PhilippinePiper betle leaves. Arch. Pharm. Res. 9, 93–97 (1986). https://doi.org/10.1007/BF02857217
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DOI: https://doi.org/10.1007/BF02857217