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Effects of hypervitaminosis of vitamin B3 on silkworm biology

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Abstract

A high-dose of vitamin B3 in silkworm diet interrupts larval feeding and normal growth. High mortality of larvae occurs during molting and they cannot complete this process normally. Also the larvae exhibit nicotinamide hypervitaminosis symptoms such as immobility, dyspepsia, darkening of the skin, inability to excrete normally, exerting brownish fluid from anus and swelling of rectal muscles. Maximum larval weights in 1, 2 and 3 g/l treatments were 2.9, 1.6 and 1.2 g respectively, while maximum larval weight in the control was 5.6 g. Larval stage compared to control had increased 18, 26 and 31 days respectively. The concentration increase of uric acid in haemolymph demonstrates the hyperuricemia, while other measured biochemical compounds show significant decrease; sodium and potassium did not change significantly.

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Abbreviations

DIW:

Daily increase of weight

NAD:

nicotinamide adenine dinucleotide

NADP:

NAD phosphate

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Authors and Affiliations

  1. Department of Sericulture, Faculty of Natural Resources, University of Guilan, Somehe Sara, Iran

    Kayvan Etebari & Leila Matindoost

  2. Department of Entomology, Faculty of Agriculture, University of Guilan, Rasht, Iran

    Leila Matindoost

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  1. Kayvan Etebari
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  2. Leila Matindoost
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Correspondence to Kayvan Etebari.

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Etebari, K., Matindoost, L. Effects of hypervitaminosis of vitamin B3 on silkworm biology. J. Biosci. 29, 417–422 (2004). https://doi.org/10.1007/BF02712113

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