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Estimation of the response curve in radioligand assays

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References

  1. Arrigucci, A., Forti, G., Fiorelli, G., Pazzagli, M. and Serio, M. (1973). Mathematical analysis of the results of competitive binding methods,The Endocrine Function of the Human Testis, vol. 1, 74–90.

    Google Scholar 

  2. Burger, H. G., Lee, V. W. K. and Rennie, G. C. (1973). A generalised computer program for the treatment of data from competitive protein-binding assays including radioimmunoassays,Journal of Laboratory and Clinical Medicine,80, 302–312.

    Google Scholar 

  3. Cook, B. (1975). Automation and data processing for radioimmunoassays,Steroid Immunoassay—Proceedings of the Fifth Tenovus Workshop, Alpha Omega Publishing Ltd., Cardiff, 293–310.

    Google Scholar 

  4. Ekins, R. and Newman, B. (1970). Theoretical aspects of saturation analysis,Acta Endocrinologica, suppl.147, 11–36.

    Google Scholar 

  5. Finney, D. J. (1964).Statistical Methods in Biological Assay (2nd edition), Charles Griffin & Co. Ltd., London.

    Google Scholar 

  6. Finney, D. J. (1971).Probit Analysis (3rd edition), The University Press, Cambridge.

    MATH  Google Scholar 

  7. Finney, D. J. (1976). Radioligand assay,Biometrics,32, 721–740.

    Article  Google Scholar 

  8. Harding, B. R., Thomson, R. and Curtis, A. R. (1973). A new mathematical model for fitting and HPL radioimmunoassay curve,Journal of Clinical Pathology,26, 973–976.

    Google Scholar 

  9. Healy, M. J. R. (1972). Statistical analysis of radioimmunoassay data,Biochemical Journal,130, 207–210.

    Google Scholar 

  10. Midgley, A. R. (1966). Radioimmunoassay: A method for human chorionic gonadotrophin and human luteinizing hormone,Endocrinology,79, 10–18.

    Article  Google Scholar 

  11. Midgley, A. R., Niswender, G. D. and Rebar, R. W. (1969). Principles for the assessment of the reliability of radioimmunoassay methods (precision, accuracy, sensitivity, specificity),Acta Endocrinologica, supplementum no.142, 163–184.

    Google Scholar 

  12. Nelder, J. A. and Mead, R. (1965). A simplex method for function minimization,Computer Journal,7, 308–313.

    MATH  Google Scholar 

  13. Rodbard, D. (1971). Statistical aspects of radioimmunoassays,Principles of Competitive Protein Binding Assays, Lippincott, Philadelphia, 204–259.

    Google Scholar 

  14. Rodbard, D. (1974). Statistical quality control and routine data processing for radio-immunoassays and immunoradiometric assays,Clinical Chemistry,20, 1255–1270.

    Google Scholar 

  15. Rodbard, D. and Cooper, J. A. (1970). A model for prediction of confidence limits in radioimmunoassays and competitive protein binding assays,Proceedings, Symposium on Radioisotopes in Medicine, 659–674.

  16. Rodbard, D. and Frazier, G. R. (1975). Statistical analysis of radioligand assay data,Methods in Enzymology,37, 3–22.

    Article  Google Scholar 

  17. Rodbard, D. and Hutt, D. M. (1974). Statistical analysis of radioimmunoassays and immunoradiometric (labelled antibody) assays: a generalized weighted, iterative, least-squares method for logistic curve fitting,Symposium on RIA and Related Procedures in Medicine,1, 165–192.

    Google Scholar 

  18. Rodbard, D., Lenox, R. H., Wray, H. L. and Ramseth, D. (1976). Statistical characterization of the random errors in the radioimmunoassay dose-response variable,Clinical Chemistry,22, 350–358.

    Google Scholar 

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Finney, D.J. Estimation of the response curve in radioligand assays. Ann Inst Stat Math 29, 467–477 (1977). https://doi.org/10.1007/BF02532806

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  • DOI: https://doi.org/10.1007/BF02532806

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