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Comparison of time risks based on a multinomial logistic response model in longitudinal studies

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Summary

The multinomial logistic response model has been used in the analysis of data from longitudinal studies of RERF's mortality cohort population. The model was restricted to linear and quadratic doseresponses for practical as well as biological reasons. The advantages and disadvantages of the multinomial logistic model are pointed out. Numerical comparison is made of the maximum likelihood (ML) estimates of parameters obtained by binomial and multinomial logistic procedures. The dose-response difference between two independent “same age” groups is evaluated from the ML estimates of parameters under a linear logistic response model. A significant dose-response difference between two independent “same age” groups in the years 1950–1959 and 1960–1969 is noted only for the 15–24 age group for all cancers other than leukemia.

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Radiation Effects Research Foundation

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Otake, M. Comparison of time risks based on a multinomial logistic response model in longitudinal studies. Ann Inst Stat Math 32, 125–142 (1980). https://doi.org/10.1007/BF02480319

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