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The possible role of solitonic processes during A to B conformational changes in DNA

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Abstract

Among the conformations which the DNA molecule can adopt, the transition beween the A and B families, controlled by water content (relative humidity), seems to be implicated in the transcription process. Focusing on the main structural difference involved (tilting of base normals with respect to the helix axis), a model is constructed, solitary wave solutions of the resulting equation of motion are demonstrated and possible experimental implications indicated.

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Khan, A., Bhaumik, D. & Dutta-Roy, B. The possible role of solitonic processes during A to B conformational changes in DNA. Bltn Mathcal Biology 47, 783–789 (1985). https://doi.org/10.1007/BF02469305

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  • DOI: https://doi.org/10.1007/BF02469305

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