Skip to main content
Log in

Axonal transport—II. Convection

  • Published:
Bulletin of Mathematical Biology Aims and scope Submit manuscript

Abstract

The phenomenon of axonal transport has been well documented (Ochs, 971; Lasek, 1970; and Grafstein, 1967). In a previous paper, we showed how diffusion alone could not account for this process. In this report we show that convection or convection with diffusion can account for the observed build-up of material. By including a first-order catabolic sequestration term, we are able to offer an understanding of the several apparent rates of transport with the same underlying velocity and variable sequestration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature

  • Bradley, W. G. and E. Jaros. 1973. “Axoplasmic flow in axonal neuropathies II. Axoplasmic flow in mice with motor neuron disease and muscular dystrophy.”Brain,96, 247–258.

    Google Scholar 

  • Droz, B., H. L. Koenig and L. D. Giamberdino. 1973. “Axonal Migration of Protein and Glycoprotein to Nerve Ending I.”Brain Res.,60, 93–127.

    Article  Google Scholar 

  • Grafstein, B. 1967. “Transport of Protein by the Goldfish Optic Nerve Fibers.”Science,157, 196–198.

    Google Scholar 

  • Gross, G. W. and L. M. Beidler. 1973. “Past Axonal Transport in theC fibers of the Garfish olfactory nerve.”J. Neurobiol.,4, 413–428.

    Article  Google Scholar 

  • Lasek, R. 1970. “Protein Transport in Neurons.”Int. Rev. Neurobiol.,13, 289–324.

    Article  Google Scholar 

  • McEwan, B. S. and B. Grafstein 1968. “Fast and Slow Components in Axonal Transport of Proteins.”J. Cell. Biol.,38, 494–508.

    Article  Google Scholar 

  • Ochs, S. 1971. “Characteristics and A Model for Fast Axoplasmic Transport in Nerve”.J. Neurobiol.,2, 331–345.

    Article  Google Scholar 

  • Pickering, B. T. and C. W. Jones. 1971. “The biosynthesis and intraneuronal transport of neurohypophysial hormones.”Mem. Soc. Endocrinol.,19, 337–351.

    Google Scholar 

  • Pleasure, D. E., K. C. Mishler and W. K. Engel. 1969. “Axonal transport of proteins in experimental neuropathies.”Science,166, 524–525.

    Google Scholar 

  • Schonbach, J., Ch. Schonbach and M. Cuenod, 1973. “Distribution of Transported Proteins in the Slow phase of Axoplasmic Flow: An electron microscopical autoradiographical study.”J. Comp. Neurol.,152, 1–17.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Copeland, A.R. Axonal transport—II. Convection. Bltn Mathcal Biology 38, 435–444 (1976). https://doi.org/10.1007/BF02462217

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02462217

Keywords

Navigation