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Simulation of cellular compaction and internalization in mammalian embryo development as driven by minimization of surface energy

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Abstract

A model based upon minimization of surface energy is proposed as an explanation for compaction and internalization of cells during mammalian embryo development. The model is used to simulate and graphically display these phenomena on a computer.

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Author notes

  1. Carlos F. Doggenweiler (Fulbright Scholar)

    Present address: Department of Biology, University of Chile, Casilla 653, Santiago, Chile

  2. Richard L. Thompson

    Present address: La Jolla Institute, P.O. Box 1434, 92038, La Jolla, CA, USA

Authors and Affiliations

  1. Department of Systems Science, State University of New York, Binghamton, 13901, New York, NY, USA

    Narendra S. Goel & Carlos F. Doggenweiler (Fulbright Scholar)

  2. Cavendish Laboratory, Madingley Road, CB3 0HE, Cambridge, England

    Richard L. Thompson

Authors
  1. Narendra S. Goel
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  2. Carlos F. Doggenweiler
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  3. Richard L. Thompson
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Goel, N.S., Doggenweiler, C.F. & Thompson, R.L. Simulation of cellular compaction and internalization in mammalian embryo development as driven by minimization of surface energy. Bltn Mathcal Biology 48, 167–187 (1986). https://doi.org/10.1007/BF02460021

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  • DOI: https://doi.org/10.1007/BF02460021

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