Skip to main content
Log in

Multiple solutions of a model describing cancerous growth

  • Published:
Bulletin of Mathematical Biology Aims and scope Submit manuscript

Abstract

Multiple solutions of a model describing immune surveillance against cancer are studied. The model was proposed by R. Lefever and co-workers. A limit cycle solution and two kinds of wave front solutions are worked out by means of a perturbation method. The problem of nucleation concerning this model is studied by a singular-perturbation technique. In addition, the pulse wave solution is also found by numerical simulations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature

  • Gatti, R. A., W. W. Robison, A. S. Deinare, M. Nesbit, J. J. McCullough, M. Ballow and R. A. Good. 1973. Cyclic Leukocytosis in Chronic Myelogenous Leukemia.Blood 41, 771–782.

    Google Scholar 

  • Lefever, R. and T. Erneux. 1984. “On the Growth of Cellular Tissues under Constant and Fluctuating Environmental Conditions.” InNonlinear Electrodynamics in Biological Systems. W. Ross and A. Lawrence (Eds), p. 287. Plenum Publishing Corporation.

  • Lefever, R. and R. Garay. 1978. “Local Description of Immune Tumour Rejection.” InBiomathematics and Cell Kinetics, pp. 333–334. North Holland.

  • Lefever, R. and J. Hiernaux. 1985. “Annual Scientific Progress Report 1984 to 1985”.

  • Nicolis, G. and I. Prigogine. 1977.Self-Organization in Non-equilibrium Systems. New York: Wiley.

    Google Scholar 

  • Nitzan, A., P. Ortoleva and J. Ross. 1974. “Nucleation in Systems with Multiple Stationery States.” InSymposia of the Faraday Society, No. 9, pp. 241–253. London: Faraday Division Chemical Society.

    Google Scholar 

  • Prigogine, I. and R. Lefever. 1980. “Stability Problems in Cancer Growth and Nucleation.”Comp. Biochem. Physiol. 67B, 389–393.

    Google Scholar 

  • Qi, A. S. 1981. “Non-equilibrium Phase Transitions in a Reaction-Diffusion Description of Tissue Growth.” Ph.D. Thesis, Brussels Liberty University.

  • —. 1985. “The Nucleation Problem in Schlögl Model of First Order Phase Transition.”Acta Physica Sinica 34,(9), 1178–1184.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Qi, AS. Multiple solutions of a model describing cancerous growth. Bltn Mathcal Biology 50, 1–17 (1988). https://doi.org/10.1007/BF02459974

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02459974

Keywords

Navigation