Abstract
Multiple solutions of a model describing immune surveillance against cancer are studied. The model was proposed by R. Lefever and co-workers. A limit cycle solution and two kinds of wave front solutions are worked out by means of a perturbation method. The problem of nucleation concerning this model is studied by a singular-perturbation technique. In addition, the pulse wave solution is also found by numerical simulations.
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Gatti, R. A., W. W. Robison, A. S. Deinare, M. Nesbit, J. J. McCullough, M. Ballow and R. A. Good. 1973. Cyclic Leukocytosis in Chronic Myelogenous Leukemia.Blood 41, 771–782.
Lefever, R. and T. Erneux. 1984. “On the Growth of Cellular Tissues under Constant and Fluctuating Environmental Conditions.” InNonlinear Electrodynamics in Biological Systems. W. Ross and A. Lawrence (Eds), p. 287. Plenum Publishing Corporation.
Lefever, R. and R. Garay. 1978. “Local Description of Immune Tumour Rejection.” InBiomathematics and Cell Kinetics, pp. 333–334. North Holland.
Lefever, R. and J. Hiernaux. 1985. “Annual Scientific Progress Report 1984 to 1985”.
Nicolis, G. and I. Prigogine. 1977.Self-Organization in Non-equilibrium Systems. New York: Wiley.
Nitzan, A., P. Ortoleva and J. Ross. 1974. “Nucleation in Systems with Multiple Stationery States.” InSymposia of the Faraday Society, No. 9, pp. 241–253. London: Faraday Division Chemical Society.
Prigogine, I. and R. Lefever. 1980. “Stability Problems in Cancer Growth and Nucleation.”Comp. Biochem. Physiol. 67B, 389–393.
Qi, A. S. 1981. “Non-equilibrium Phase Transitions in a Reaction-Diffusion Description of Tissue Growth.” Ph.D. Thesis, Brussels Liberty University.
—. 1985. “The Nucleation Problem in Schlögl Model of First Order Phase Transition.”Acta Physica Sinica 34,(9), 1178–1184.
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Qi, AS. Multiple solutions of a model describing cancerous growth. Bltn Mathcal Biology 50, 1–17 (1988). https://doi.org/10.1007/BF02459974
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DOI: https://doi.org/10.1007/BF02459974