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Autocatalytic networks with translation

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Abstract

We consider the kinetics of an autocatalytic reaction network in which replication and catalytic actions are separated by a translation step. We find that the behaviour of such a system is closely related to second-order replicator equations, which describe the kinetics of autocatalytic reaction networks in which the replicators act also as catalysts. In fact, the qualitative dynamics seems to be described almost entirely be the second-order reaction rates of the replication step. For two species we recover the qualitative dynamics of the replicator equations. Larger networks show some deviations, however. A hypercyclic system consisting of three interacting species can converge toward a stable limit cycle in contrast to the replicator equation case. A singular perturbation analysis shows that the replication-translation system reduces to a second-order replicator equation if translation is fast. The influence of mutations on replication-translation networks is also very similar to the behavior of selection-mutation equations.

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Authors and Affiliations

  1. Theoretische Biochemie, Institut für Theoretische Chemie, Universität Wien, Vienna, Austria

    Robert Happel & Robert Hecht

  2. Santa Fe Institute, 87501, Santa Fe, NM, U.S.A.

    Peter F. Stadler

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  1. Robert Happel
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  2. Robert Hecht
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  3. Peter F. Stadler
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Happel, R., Hecht, R. & Stadler, P.F. Autocatalytic networks with translation. Bltn Mathcal Biology 58, 877–905 (1996). https://doi.org/10.1007/BF02459488

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  • DOI: https://doi.org/10.1007/BF02459488

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