Abstract
A model of morphogenetic pattern formation recently proposed by Frenchet al. (1976) is investigated in relation to the properties of reaction-diffusion systems operating on two-dimensional circular medium. One of the basic requirements of this model is the existence of a circular morphogenetic gradient exhibiting no discontinuity. We explain how bifur-cation theory may account for the generation of such a spatial pattern through reaction-diffusion processes. For this, we study the emergence of multiple-order bifurcations.
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Literature
Auchmuty, J. F. G. and G. Nicolis. 1975. “Bifurcation Analysis of Nonlinear Reaction-Diffusion Equations—I Evolution Equations and the Steady State Solutions”.Bull. Math. Biol.,37, 323–365.
Babloyantz, A. and J. Hiernaux. 1975. “Models for Cell Differentiation and Generation of Polarity in Diffusion Governed Morphogenetic Fields”.Bull. Math. Biol.,37, 637–657.
Cooke, J. 1975. “The Emergence and Regulation of Spatial Organization in Early Animal Development”.Ann. Rev. Biophys. Bioengng,4, 185–217.
Fife, P. C. 1977. “Stationary Patterns for Reaction-Diffusion Equations”.Res. Notes Math. 14, 81–122.
French, V., P. J. Bryant and S. V. Bryant. 1976. “Pattern Regulation in Epimorphic Fields”.Science,193, 969–981.
Gierer, A. 1977. “Biological Features and Physical Concepts of Pattern Formation Exemplified by Hydra”.Curr. Topics Dev. Biol.,11, 17–57.
Gierer, A. and H. Meinhardt. 1972. “A Theory of Biological Pattern Formation”.Kybernetic,12, 30–39.
Herschkowitz-Kaufman, M. and T. Erneux. 1979. “The Bifurcation Diagram of Model Chemical Reactions”. To appear inAnn. N.Y. Acad. Sci.
Hiernaux, 1976. “Modèles Théoriques de la Différenciation Cellulaire et de la Morphogénèse”. Ph. D. Thesis, Université Libre de Bruxelles.
Kauffman, S. A., R. M. Shymko and K. Trabert. 1978. “Control of Sequential Compartment Formation inDrosophila”.Science 199, 259–270.
Keener, J. P. 1976. “Secondary Bifurcations in Nonlinear Diffusion-Reaction Equations”.Stud. Appl. Math.,55, 187–211.
MacDonald, N. 1977. “A Polar Coordinate System for Positional Information in the Vertebrate Neural Retina”.J. Theor. Biol.,69, 153–165.
Maden, M. and R. N. Turner. 1978. “Supernumerary Limbs in the Axolotl”.Nature,273, 232–235.
Mahar, T. J. and B. J. Matkowsky 1977. “A Model Biochemical Reaction Exhibiting Secondary Bifurcation”.SIAM J. Appl. Math.,32, 394–404.
Meinhardt, H. 1977. “A Model of Pattern Formation in Insect Embryogenesis”.J. Cell Sci.,23, 117–139.
Meinhardt, H. and A. Gierer. 1975. “Application of a Theory of Biological Pattern Formation Based on Lateral Inhibition”.J. Cell. Sci. 15, 321–346.
Othmer, H. 1977. “Current Theories of Pattern Formation”.Lect. Math. Life Sci.,9, 57–87.
Pavlidis, T. 1975. “Spatial Organization of Chemical Oscillations via an Averaging Operator”.J. Chem. Phys.,63, 5269–5273.
Slack, J. and S. Savage. 1978. “Regeneration of Reduplicated Limbs in Contravention of the Complete Circular Rule”.Nature,271, 760–761.
Stocum, D. L. 1978. “Regeneration of Symmetrical Hindlimbs in Larval Salamanders”.Science,200, 790–793.
Turing, A. M. 1952. “The Chemical Basis of Morphogenesis”.Phil. Trans. R. Soc., Lond.,B237, 37–72.
Winfree, A. 1974. “Wavelike Activity in Biological and Chemical Media”. In:Lecture Notes in Biomathematics, Ed. P. Van den Driessche, Berlin: Springer.
Wolpert, L. 1969. “Positional Information and the Spatial Pattern of Cellular Differentiation”.J. Theor. Biol.,25, 1–47.
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Hiernaux, J., Erneux, T. Chemical patterns in circular morphogenetic fields. Bltn Mathcal Biology 41, 461–468 (1979). https://doi.org/10.1007/BF02458324
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DOI: https://doi.org/10.1007/BF02458324