Skip to main content
Log in

Chemical patterns in circular morphogenetic fields

  • Published:
Bulletin of Mathematical Biology Aims and scope Submit manuscript

Abstract

A model of morphogenetic pattern formation recently proposed by Frenchet al. (1976) is investigated in relation to the properties of reaction-diffusion systems operating on two-dimensional circular medium. One of the basic requirements of this model is the existence of a circular morphogenetic gradient exhibiting no discontinuity. We explain how bifur-cation theory may account for the generation of such a spatial pattern through reaction-diffusion processes. For this, we study the emergence of multiple-order bifurcations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature

  • Auchmuty, J. F. G. and G. Nicolis. 1975. “Bifurcation Analysis of Nonlinear Reaction-Diffusion Equations—I Evolution Equations and the Steady State Solutions”.Bull. Math. Biol.,37, 323–365.

    Article  MATH  MathSciNet  Google Scholar 

  • Babloyantz, A. and J. Hiernaux. 1975. “Models for Cell Differentiation and Generation of Polarity in Diffusion Governed Morphogenetic Fields”.Bull. Math. Biol.,37, 637–657.

    Article  MATH  Google Scholar 

  • Cooke, J. 1975. “The Emergence and Regulation of Spatial Organization in Early Animal Development”.Ann. Rev. Biophys. Bioengng,4, 185–217.

    Article  Google Scholar 

  • Fife, P. C. 1977. “Stationary Patterns for Reaction-Diffusion Equations”.Res. Notes Math. 14, 81–122.

    Google Scholar 

  • French, V., P. J. Bryant and S. V. Bryant. 1976. “Pattern Regulation in Epimorphic Fields”.Science,193, 969–981.

    Google Scholar 

  • Gierer, A. 1977. “Biological Features and Physical Concepts of Pattern Formation Exemplified by Hydra”.Curr. Topics Dev. Biol.,11, 17–57.

    Article  Google Scholar 

  • Gierer, A. and H. Meinhardt. 1972. “A Theory of Biological Pattern Formation”.Kybernetic,12, 30–39.

    Article  Google Scholar 

  • Herschkowitz-Kaufman, M. and T. Erneux. 1979. “The Bifurcation Diagram of Model Chemical Reactions”. To appear inAnn. N.Y. Acad. Sci.

  • Hiernaux, 1976. “Modèles Théoriques de la Différenciation Cellulaire et de la Morphogénèse”. Ph. D. Thesis, Université Libre de Bruxelles.

  • Kauffman, S. A., R. M. Shymko and K. Trabert. 1978. “Control of Sequential Compartment Formation inDrosophila”.Science 199, 259–270.

    Google Scholar 

  • Keener, J. P. 1976. “Secondary Bifurcations in Nonlinear Diffusion-Reaction Equations”.Stud. Appl. Math.,55, 187–211.

    MATH  MathSciNet  Google Scholar 

  • MacDonald, N. 1977. “A Polar Coordinate System for Positional Information in the Vertebrate Neural Retina”.J. Theor. Biol.,69, 153–165.

    Article  MathSciNet  Google Scholar 

  • Maden, M. and R. N. Turner. 1978. “Supernumerary Limbs in the Axolotl”.Nature,273, 232–235.

    Article  Google Scholar 

  • Mahar, T. J. and B. J. Matkowsky 1977. “A Model Biochemical Reaction Exhibiting Secondary Bifurcation”.SIAM J. Appl. Math.,32, 394–404.

    Article  MATH  MathSciNet  Google Scholar 

  • Meinhardt, H. 1977. “A Model of Pattern Formation in Insect Embryogenesis”.J. Cell Sci.,23, 117–139.

    Google Scholar 

  • Meinhardt, H. and A. Gierer. 1975. “Application of a Theory of Biological Pattern Formation Based on Lateral Inhibition”.J. Cell. Sci. 15, 321–346.

    Google Scholar 

  • Othmer, H. 1977. “Current Theories of Pattern Formation”.Lect. Math. Life Sci.,9, 57–87.

    MATH  MathSciNet  Google Scholar 

  • Pavlidis, T. 1975. “Spatial Organization of Chemical Oscillations via an Averaging Operator”.J. Chem. Phys.,63, 5269–5273.

    Article  Google Scholar 

  • Slack, J. and S. Savage. 1978. “Regeneration of Reduplicated Limbs in Contravention of the Complete Circular Rule”.Nature,271, 760–761.

    Article  Google Scholar 

  • Stocum, D. L. 1978. “Regeneration of Symmetrical Hindlimbs in Larval Salamanders”.Science,200, 790–793.

    Google Scholar 

  • Turing, A. M. 1952. “The Chemical Basis of Morphogenesis”.Phil. Trans. R. Soc., Lond.,B237, 37–72.

    Google Scholar 

  • Winfree, A. 1974. “Wavelike Activity in Biological and Chemical Media”. In:Lecture Notes in Biomathematics, Ed. P. Van den Driessche, Berlin: Springer.

    Google Scholar 

  • Wolpert, L. 1969. “Positional Information and the Spatial Pattern of Cellular Differentiation”.J. Theor. Biol.,25, 1–47.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hiernaux, J., Erneux, T. Chemical patterns in circular morphogenetic fields. Bltn Mathcal Biology 41, 461–468 (1979). https://doi.org/10.1007/BF02458324

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02458324

Keywords

Navigation