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Changes in gene expression of cholecystokinin-A receptor after induction of pancreatitis by pancreatic duct occlusion in rats

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Abstract

Serial changes in the levels of cholecystokinin (CCK)-A receptor mRNA in the pancreas after pancreatic duct occlusion were examined in rats. CCK-A receptor mRNA level was determined by Northern blot analysis with a rat CCK-A-receptor cDNA probe. The level of CCK-A receptor mRNA first decreased, reaching the lowest level 7 days after occlusion, and then began to increase. On day 14, it had completely recovered to the control level and it remained at that level until 28 days after occlusion.

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Miyasaka, K., Funakoshi, A. Changes in gene expression of cholecystokinin-A receptor after induction of pancreatitis by pancreatic duct occlusion in rats. J Gastroenterol 30, 683–685 (1995). https://doi.org/10.1007/BF02367799

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  • DOI: https://doi.org/10.1007/BF02367799

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