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Interaction of aminoquinolines with unsaturated carboxylic acids. 1. Synthesis of N-quinolyl-β-alanines and their biological activity

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

N-Quinolyl-β-alanines, and α-methyl- and-methyl-N-quinolyl-β-alanines were prepared by reaction of aminoquinolines and acrylic, methacrylic, and crotonic acids. The corresponding hydrazides and benzylidenehydrazides were obtained. 4-Aminoquinoline with unsaturated acids in water gave betaines. The biological activity of sodium salts of β-alanines was investigated.

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Authors
  1. Z. J. Beresnevicius
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  2. V. Viliunas
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  3. K. Kantminiene
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Additional information

Kaunas University of Technology, Kaunas LT-3028, Lithuania; Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 504–511, April, 2000.

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Beresnevicius, Z.J., Viliunas, V. & Kantminiene, K. Interaction of aminoquinolines with unsaturated carboxylic acids. 1. Synthesis of N-quinolyl-β-alanines and their biological activity. Chem Heterocycl Compd 36, 432–438 (2000). https://doi.org/10.1007/BF02269541

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  • DOI: https://doi.org/10.1007/BF02269541

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