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Oxidative activity of organometallic compounds in relation to the coenzymes NADH and NADPH

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Kinetic investigations of the interaction of Hg and Sn-containing organometallic compounds with NADH and NADPH using spectro-photometric methods have shown that these compounds may act as oxidizing agents in relation to the coenzyme. Their oxidative activity depends on the nature and number of organic groups in the molecule. Comparison of the kinetic data for the activity of Hg and Sn compounds with those for Fe porphyrins imitating the active centers of redox enzymes indicates the competitiveness of the organometallic compounds and models of natural electron acceptors.

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Authors
  1. M. V. Medvedev
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  2. V. Yu. Tyurin
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  3. E. A. Rozhkova
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  4. E. R. Milaeva
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Additional information

M. V. Lomonosov Moscow State University, Moscow 119899, Russia Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1036–1040, August, 1999.

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Medvedev, M.V., Tyurin, V.Y., Rozhkova, E.A. et al. Oxidative activity of organometallic compounds in relation to the coenzymes NADH and NADPH. Chem Heterocycl Compd 35, 907–911 (1999). https://doi.org/10.1007/BF02252158

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  • DOI: https://doi.org/10.1007/BF02252158

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