Skip to main content
SpringerLink
Log in

Heterocycles containing nitrogen and sulfur. Part 49. Synthesis of derivatives of new heterocyclic systems: 1,2-Dioxocyclopenta(hexa)[g]oxazolidino-[3,2-f] pyrimido[4,5-b][1,4]thiazine, 1,2-dioxocyclopenta(hexa)-[g] imidazolidino[3,2-f]pyrimido[4,5-b][1,4]thiazine, and 1,2-oxazino[5,4-g]pyrimidino[4,5-b][1,4]thiazine

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 4-methoxy-5-amino-6-mercaptopyrimidine with 2-oxo-1-chlorocyclopentyl(hexyl)glyoxalate esters gave derivatives of the previously unknown tetracyclic systems 1,2-dioxocyclopenta (hexa)[g]oxazolidino[3,2-f]pyrimido[4,5-b][1,4]thiazines, which are transformed by ammonium acetate into derivatives of 1,2-dioxocyclopenta(hexa) [g]imidazolidino[3,2-f]pyrimido[4,5-b]-[1,4] thiazines. Derivatives of the new tricyclic 1-oxazino [5,4-g]pyrimido[4,5-b][1,4]thiazine system were obrtained by reaction of 6-carbethoxy-7-acetylpyrimido [4,5-b] [1,4] thiazines with hydroxylamine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. N. P. Solov'eva, O. S. Anisimova, E. M. Peresleni, K. F. Turchin, Yu. N. Sheinker, L. G. Levkovskaya, L. A. Serochkina, and T. S. Safonova, Khim. Geterotsikl. Soedin., No.8, 1133 (1993).

    Google Scholar 

  2. L. G. Levkovskaya, I. E. Mamaeva, O. S. Anisimova, and T. S. Safonova, Khim. Geterotsikl. Soedin., No. 2, 250 (1979).

    Google Scholar 

  3. T. S. Safonova, J. N. Sheinker, M. P. Nemerjuck, E. M. Peresleni, and G. P. Syrova, Tetrahedron,27, 5453 (1971).

    Google Scholar 

  4. L. G. Levkovskaya, I. E. Mamaeva, L. A. Serochkina, and T. S. Safonova, Khim. Geterotsikl. Soedin., No. 7, 992 (1986).

    Google Scholar 

  5. L. G. Levkovskaya, I. E. Mamaeva, L. A. Serochkina, and T. S. Safonova, Khim. Geterotsikl. Soedin., No.6, 772 (1983).

    Google Scholar 

  6. A. Mondon, J. Zander, and H.-U. Menz, Lieb. Ann. Chem.,667, 126 (1963).

    Google Scholar 

Download references

Authors
  1. T. S. Safonova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. E. Mamaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

See [1] for Part 48.

Medicinal Substances Chemistry Center, All-Russia Chemical and Pharmaceutical Research Institute, Moscow 119815. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 101–104, January, 1999.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Safonova, T.S., Mamaeva, I.E. Heterocycles containing nitrogen and sulfur. Part 49. Synthesis of derivatives of new heterocyclic systems: 1,2-Dioxocyclopenta(hexa)[g]oxazolidino-[3,2-f] pyrimido[4,5-b][1,4]thiazine, 1,2-dioxocyclopenta(hexa)-[g] imidazolidino[3,2-f]pyrimido[4,5-b][1,4]thiazine, and 1,2-oxazino[5,4-g]pyrimidino[4,5-b][1,4]thiazine. Chem Heterocycl Compd 35, 97–100 (1999). https://doi.org/10.1007/BF02251671

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02251671

Keywords

Search

Navigation