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Tissue parameters determining the visual appearance of normal skin and port-wine stains

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Abstract

Port-wine stain is a congenital birthmark consisting of an abnormal density of blood vessels in the upper dermis. The enlarged blood volume gives the lesion a red to purple colour. The aim of the treatments is to destroy the vessels to the extent necessary for obtaining a normal skin coloration. Thus, in principle, all relevant information about the lesion should be contained in a reflectance spectrum in the visible. However, the relation between the reflectance spectrum and tissue parameters such as scattering, melanin content and blood distribution is somewhat composite. This work tries to enlighten this relation in terms of a very simple analytical mathematical model, and it is demonstrated that such a model at least will contribute to a qualitative understanding of the relevance of the various parameters.

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References

  1. Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation.Science 1983,220:524–7

    PubMed  Google Scholar 

  2. Nelson JS, Milner TE, Anvari B et al. Dynamic cooling during pulsed laser treatment of port wine stain—a new methodology with preliminary clinical evaluation.Arch Dermatol (in press)

  3. Svaasand LO, Milner TE, Anvari B et al. Epidermal heating during laser induced photothermolysis of port wine stains: modeling melanosomal heating after dynamic cooling the skin surface.SPIE Europto Series 1994,2323:366–77

    Google Scholar 

  4. Ishimaru A.Wave Propagation and Scattering in Random Media. New York: Academic Press, 1978:66

    Google Scholar 

  5. Steinke JM, Shepherd AP. Diffusion model of the optical absorbance of whole blood.J Opt Soc Am 1988,5:813–22

    Google Scholar 

  6. Hillenkamp F. Interaction between laser radiation and biological systems. In: Hillenkamp F, Pratesi R, Sacci C (eds)Lasers in Biology and Medicine.New York: Plenum Press, 1979:57, 61

    Google Scholar 

  7. van Gemert MJC, Welch AJ. Clinical use of lasertissue interactions.IEEE Eng Med Biol Magazine 1989,8(4):10–3

    Article  Google Scholar 

  8. van Gemert MJC, Jacques SL, Sterenborg HJCM, Star WM. Skin optics.IEEE Trans Biomed Eng 1989,36:1146–54

    Article  PubMed  Google Scholar 

  9. Wan S, Anderson RR, Parrish JA. Analytical modeling for the optical properties of the skin in vitro and in vivo applications.Photochem Photobiol 1981,34:493–9

    PubMed  Google Scholar 

  10. Anderson RR, Parrish JA. Optical properties of human skin. In: Regan JD, Parrish JA (eds)The Science of Photomedicine. New York: Plenum Press, 1982:147–194

    Google Scholar 

  11. Duck FA.Physical Properties of Tissue. London: Academic Press, 1990

    Google Scholar 

  12. Hruza GJ, Dover JS, Flotte TJ et al. Q-switched ruby laser irradiation of normal human skin.Arch Dermatol 1991,127:1799–805

    Article  PubMed  Google Scholar 

  13. Moschella SL, Hurley HJ. Dermatology, 3rd edn. London: W. B. Saunders, 1992:1421–35

    Google Scholar 

  14. Jacques SL, McAuliffe DJ. The melanosome: threshold temperature for explosive vaporization and internal absorption coefficient during laser irradiation.Photochem Photobiol 1991,6:769–75

    Google Scholar 

  15. Scheuplein RJ. A survey of some fundamental aspects of the absorption and reflection of light by tissue.J Soc Cos Chem 1964,15:11–122

    Google Scholar 

  16. Haskell RC, Svaasand LO, Tsay T-T et al. Boundary conditions for the diffusion equation in radiative transfer.J Opt Soc Am 1994,11:2727–41

    Google Scholar 

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Svaasand, L.O., Norvang, L.T., Fiskerstrand, E.J. et al. Tissue parameters determining the visual appearance of normal skin and port-wine stains. Laser Med Sci 10, 55–65 (1995). https://doi.org/10.1007/BF02133165

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  • DOI: https://doi.org/10.1007/BF02133165

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