Summary
The corticotropin-releasing activity of synthetic corticoliberin increases 75–90% when it is incubated in the presence of arginine vasopressin with rat anterior pituitary cell suspensions; this suggests a synergistic control of ACTH secretion by vasopressin and corticoliberin.
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Acknowledgments. This study was supported by grant No. 3.581-0.79 of the Swiss National Science Foundation. We thank Ms C. Estoppey for technical assistance. Reprint requests should be addressed to A. B.
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Bény, J.L., Baertschi, A.J. Synthetic corticoliberin needs arginine vasopressin for full corticotropin releasing activity. Experientia 38, 1078–1079 (1982). https://doi.org/10.1007/BF01955377
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DOI: https://doi.org/10.1007/BF01955377