Abstract
Changes in hepatic morphology were evaluated in 242 consecutive liver biopsy specimens obtained from nonalcoholic obese subjects. Steatosis occurred in 59.7% of the subjects but was moderate to severe in 28.7%. An alcoholic hepatitis-like picture was present in 8.7% and cirrhosis in 2.7%. Fibrosis of mild and moderate degrees was encountered in 26.1% and 5.8%, respectively. This study indicates that the histopathological changes that occur in the livers of obese subjects are similar to alcoholic liver injury.
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Nasrallah, S.M., Wills, C.E. & Galambos, J.T. Hepatic morphology in obesity. Digest Dis Sci 26, 325–327 (1981). https://doi.org/10.1007/BF01308373
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DOI: https://doi.org/10.1007/BF01308373