Digestive Diseases and Sciences

, Volume 32, Issue 12, pp 1337–1344

Effects of meal composition on gallbladder and gastric emptying in man

  • Robert S. Fisher
  • Elizabeth Rock
  • Leon S. Malmud
Original Articles

DOI: 10.1007/BF01296658

Cite this article as:
Fisher, R.S., Rock, E. & Malmud, L.S. Digest Dis Sci (1987) 32: 1337. doi:10.1007/BF01296658

Abstract

Cholecystogastric scintigraphy, utilizing [99mTc]HlDA to label the gallbladder contents and [111In]DTPA to label different meals, was utilized to determine the relationships between gallbladder and gastric emptying after meals of differing composition. Gallbladder emptying was determined in response to a multicomponent meal and to monocomponent fat, carbohydrate, and protein meals and in response to isotonic and hypertonic dextrose and isotonic and hypertonic saline. Also, the gallbladder emptying responses to equivalent multicomponent solid and liquid meals were compared. Significant gallbladder emptying was observed in response to the multicomponent meal and the monocomponent fat, carbohydrate, and protein meals. The most rapid and complete gallbladder emptying was seen with the multicomponent meal and the monocomponent fat meal. Significant gallbladder emptying was stimulated, not only by isotonic and hypertonic dextrose, but also by hypertonic saline. The gallbladder emptied more rapidly after a liquid than after a solid meal.

Key Words

cholecystogastric scintigraphygallbladder emptyinggastric emptyingmulticomponent mealmonocomponent meal

Copyright information

© Plenum Publishing Corporation 1987

Authors and Affiliations

  • Robert S. Fisher
    • 1
  • Elizabeth Rock
    • 1
  • Leon S. Malmud
    • 1
  1. 1.Department of Medicine and Diagnostic ImagingTemple University School of MedicinePhiladelphia
  2. 2.Gastroenterology SectionTemple University HospitalPhiladelphia