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Phosphoryl amino acids: Common origin for nucleic acids and protein

  • Section 9. Origin And Structure Of The Cell: Chemical Aspects
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Abstract

A series of compounds (DAP-AA) composed of an amino acid (AA) and a dialkyl phosphoryl group (DAP) is the basic elements of life chemistry. Self-catalysis of DAP-AA gives the self-assembly oligopeptides, even in aqueous medium at 38°C. The oligo-nucleotides could also be assembled from nucleosides' phosphorylation by DAP-AA. DAP-AA acts as the energy source as well as the phosphoryl donor for the synthesis of nuclic Acids and protein. A general expression for the self assembly system is proposed.

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Authors and Affiliations

  1. Department of Chemistry, Laboratory of Bio-organic Phosphorus Chemistry, Tsinghua University, 100084, Beijing, People's Republic of China

    Yu-Fen Zhao & Pei-sheng Cao

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  1. Yu-Fen Zhao
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  2. Pei-sheng Cao
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Zhao, YF., Cao, Ps. Phosphoryl amino acids: Common origin for nucleic acids and protein. J Biol Phys 20, 283–287 (1995). https://doi.org/10.1007/BF00700446

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  • DOI: https://doi.org/10.1007/BF00700446

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