Summary
Renal vasodilation observed in canine endotoxemia did not occur during endotoxin shock in the baboon: in fact, renal artery blood flow was markedly reduced. Infusion of dopamine in the baboon restored the renal artery blood flow.
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References
Bell C., Conway E. L. and Land W. J.: Ergometrine and apomorphine as selective antagonists of dopamine in the canine renal vasculature. Br. J. Pharmac52, 591–595 (1974).
Brobmann G. F., Ulano H. B., Hinshaw L. B., and Jacobsen E. D.: Mesenteric vascular responses to endotoxin in monkey and dog. Amer. J. Physiol.219, 1464–1467 (1970).
Cavanagh D., Rao P. S., Sutton D., Bhagat B. D., and Bachmann F.: Pathophysiology of endotoxin shock in the primate. Amer. J. Obstet. Gynec.108, 705–722, 1970.
Goldberg L. I.: Cardiovascular and renal actions of dopamine: potential clinical applications. Pharmac. Rev.24, 1–29 (1972).
Hinshaw L. B., Bradley G. M.: Alterations in kidney weight produced by Escherichia Coli endotoxin. Amer. J. Physiol.189, 328–330, (1957).
Isakson P. C., Shofer F., McKnight R. C., Feldhaus R. A., Rax A and Needleman P.: Prostaglandins and the renin-angiotensin system in canine endotoxemia. J. Pharmacol. Exp. Ther.200, 614–622, 1977.
McDonald R. H. and Goldberg L. I.: Analysis of the cardiovascular effects of dopamine in the dog. J. Pharmacol. Exp. Ther.140, 60–66, (1963).
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Rao, P.S., Bhagat, B. Effect of dopamine on renal blood flow of baboon in endotoxin shock. Pflügers Arch. 374, 105–106 (1978). https://doi.org/10.1007/BF00585704
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DOI: https://doi.org/10.1007/BF00585704