Skip to main content
SpringerLink
Log in

Isozyme variability in species of the genus Drosophila. I. A multiple allelic isozyme system in Drosophila busckii: Inheritance and general considerations

  • Published:
Biochemical Genetics Aims and scope Submit manuscript

Abstract

Starch gel electrophoretic analysis of a triallelic leucine aminopeptidase polymorphism in a laboratory population of Drosophila busckii is described. The three alleles involved are expressed without dominance. A series of single-pair matings revealed an excess of heterozygous types in most segregating families, suggesting selection against the homozygous genotypes. A few cases of heterogeneity among progeny extracted from a single family were the result of matings that produced Mendelian ratios. These few cases had no clear genetic explanation, but there is a suggestion of two isoalleles for the electrophoretically intermediate enzyme.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Beckman, L., and Johnson, F. M. (1964a). Variations in larval alkaline phosphatase controlled by Aph alleles in Drosophila melanogaster. Genetics 49 829–835.

    Google Scholar 

  • Beckman, L., and Johnson, F. M. (1964b). Genetic control of aminopeptidase in Drosophila melanogaster. Hereditas 51 221–230.

    Google Scholar 

  • Johnson, F. M., and Sakai, R. K. (1964). A leucine aminopeptidase polymorphism in Drosophila busckii. Nature 203 373–374.

    Google Scholar 

  • Poulik, M. D. (1957). Starch gel electrophoresis in a discontinuous system of buffers. Nature 180 1477–1479.

    Google Scholar 

  • Richardson, R. H., and Johnson, F. M. (1967). Isozyme variability in species of the genus Drosophila. II. A multiple allelic isozyme system in Drosophila busckii. A stable polymorphic system. Biochem. Genet., in press.

  • Shaw, C. R. (1965). Electrophoretic variation in enzymes. Science 149 936–943.

    Google Scholar 

  • Smithies, O. (1955). Zone electrophoresis in starch gels: Group variation in the serum proteins of normal human adults. Biochem. J. 61 629–641.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Genetics Foundation, Department of Zoology, University of Texas, Austin, Texas

    F. M. Johnson, Carmen G. Kanapi & R. H. Richardson

  2. Department of Genetics, University of Hawaii, Honolulu, Hawaii

    R. K. Sakai

Authors
  1. F. M. Johnson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Carmen G. Kanapi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. H. Richardson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. K. Sakai
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

The research reported here was begun at the University of Hawaii and completed at the University of Texas and was supported (in part) by Public Health Service Research Grant No. GM 11609 to W. S. Stone and M. R. Wheeler and by Training Grant No. 2 T1-GM-337-06 and GM 00337-07 to R. P. Wagner et al., from the National Institutes of Health.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Johnson, F.M., Kanapi, C.G., Richardson, R.H. et al. Isozyme variability in species of the genus Drosophila. I. A multiple allelic isozyme system in Drosophila busckii: Inheritance and general considerations. Biochem Genet 1, 35–40 (1967). https://doi.org/10.1007/BF00487734

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00487734

Keywords

Search

Navigation