Abstract
Experimental infection in mice with Dermatophilus (D.) congolensis-like microorganisms was carried out, intraperitoneally and subcutaneously. This strain had been isolated from porcine tonsil and reported to be different in some morphological and biological points from D. congolensis. Macroscopic examination revealed multiple abscesses in the peritoneal cavities, or subcutaneous abscesses after the intraperitoneal or subcutaneous injection respectively. Histopathologic examination revealed the characteristic arrangement of the neutrophils surrounding the bacterial colony and peripheral macrophages in the abscess lesions. The lesions contained many microorganisms which showed wide range of the characteristic morphologic variation such as: mycerial elements, coccoid elements and large coccoid elements with transverse or longitudinal septa. Clamydospore-like elements were sometimes found in the microcolonies in early lesions. The morphology of the lesions and the microorganisms was compared with those of other bacterias including D. congolensis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abu-Samra, M. T., 1978. The effect of prednisolonetrimethylacetate on the pathogenicity of Dermatophilus congolensis to white mice. Mycopathologia 66: 1–8.
Abu-Samra, M. T., 1978. Morphological, cultural and biochemical characteristics of Dermatophilus congolensis. Zbl. Vet. Med. B. 25: 668–688.
Azuma, R. & Bak, U. B., 1980. Isolation of Dermatophilus like micrioorganisms from swine tonsils. Proceeding 1980 international pig veterinary society congress p. 348.
Bak, U. B., Yamamoto, H. & Azuma, R. Experimental Actinomycotic abscess in mice of several strains. Nat. Inst. Anim. Hlth. Quart. 12: 232–233.
Bak, U. B., Yamamoto, H., Azuma, R. & Nakajima, Y., 1973. Development of actinomycotic abscess in mice. Nat. Inst. Anim. Hlth Qualt. 13: 149–161.
Bak, U. B. & Azuma, R., 1980. Dermatophilus infection of the porcine tonsils. Proceeding 1980 international pig veterinary society congress p. 349.
Brown, J. R., Lichtenberg, F., 1970. Experimental actinomycosis in mice. Study of pathogenesis. Arch. Pathol. 90: 391–402.
Brown, J. R., 1973. Human actinomycosis. A study of 181 subjects. Human Pathol. 4: 319–330.
Coleman, R. M. & George, L. K., 1969. Comparative pathogenicity of Actinomyces naeslundii and Actinomyces israelii. Appl. Microbiol. 18: 427–432.
Destombes, P., Mariat, F., Nazimoff, O. & Satre, J., 1961. A propos des mycetomes à Nocardia. Sabouraudia 1: 161–172.
Gale, D. & Waldron, C. A., 1955. Experimental actinomycosis with Actinomyces israelii. J. Infect, Dis. 97: 251–261.
Georg, L. K. & Coleman, R. M., 1970. Comparative pathogenicity of various actinomyces species. The actinomycetales. Gustav Fischer Verlag, Jena.
Georg, L. K., Brown, J. M., Baker, H. J. & Cassell, C. H., 1972. Actinomyces viscosus as an agent of actinomycosis in the dog. Amer. J. Vet. Res. 33: 1457–1470.
Gordon, M. A. & Edwards, M. R., 1963. Micromorphology of Dermatophilus congolensis. J. Bacteriol. 80: 1101–1115.
Koeda, T., Abe, N. & Konno, S., 1974. Experimental pseudomonas granuloma in the skin of guineapig. Natl. Inst. Anim. Hlth Quart. 14: 9–16.
Kubo, M., Osada, M. & Konno, S., 1981. Morphology of sulfur granules produced by Pseudomonas aeruginosa in cows. Natl. Inst. Anim. Hlth Quart. 21: 26–31.
Mackinnon, J. K., Conti-Díaz, I. A., Gezuele, E., Galiana, J., Hormaeche, C. & Olivera, E., 1969. Experimental botriomycosis produced by Pseudomonas aeruginosa. J. Med. Microbiol. 2: 369–372.
Meyer, E. & Verges, P., 1950. Mouse pathogenicity as a diagnostic aid in the identification of Actinomyces bovis. J. Lab. Clin. Med. 36: 667–679.
Murray, I. G., Spooner, E. T. C. & Walker, J., 1960. Experimental infection of mice with Madurella mycetomi. Trans. R. Soc. Trop. Med. Hyg. 54: 335–341.
Richard, J. L., Ritchie, A. E. & Pier, A. C., 1967. Electron microscopic anatomy of motile-phase and germinating cells of Dermatophilus congolensis. J. Gen. Microbiol. 49: 23–29.
Robboy, S. J. & Vickery, A. L. Jr., 1970. Tinctorial and morphologic properties distinguishing actinomicosis and nocardiosis. New Eng. J. Med. 282: 593–596.
Verghese, A. & Klokke, A. H., 1966. Histologic diagnosis of species of fungus causing mycetoma. Ind. J. Med. Res. 54: 526–530.
Winslow, D. J., 1959. Botryomycosis. Amer. J. Pathol. 35: 153–167.
Winslow, D. J. & Steen, F. G., 1964. Considerations in the histologic diagnosis of mycetoma. Amer. J. Pathol. 42: 164–169.
Zlotnik, H. & Buckley, H. R., 1980. Experimental production of actinomycetoma in BALB/c Mice. Infect. Immun. 29: 1141–1145.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Momotani, E., Yoshino, T., Ishikawa, Y. et al. Morphology of experimental actinomycotic abscess in mice with Dermatophilus-like microorganisms from porcine tonsil. Mycopathologia 81, 99–105 (1983). https://doi.org/10.1007/BF00436986
Issue Date:
DOI: https://doi.org/10.1007/BF00436986