Summary
In this article we describe some in vivo properties of a coldsensitive ribosomal mutant from Escherichia coli. The mutation affects the rplV gene which is the structural gene of ribosomal protein L22.
Our work shows that at 22°C, the biosynthesis of both ribosomal subunits and the maturation processing of 16S and 23S ribosomal RNA are impaired. Integration of our results in a general model of in vivo ribosomal assembly in E. coli is presented.
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Communicated by H.G. Wittmann
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Pardo, D., Vola, C. & Rosset, R. Assembly of ribosomal subunits affected in a ribosomal mutant of E. coli having an altered L22 protein. Molec. Gen. Genet. 174, 53–58 (1979). https://doi.org/10.1007/BF00433305
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DOI: https://doi.org/10.1007/BF00433305