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Immunohistochemical detection of carcinoembryonic antigen (CEA) in parotid gland carcinomas

Analysis of 52 cases

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Summary

The presence of CEA in parotid gland tumours was studied by immunohistochemical methods. 52 cases were analysed. 7 of 8 adenocarcinomas, 3 of 5 cystadenocarcinomas, 3 of 4 adenoid cystic carcinomas and all 3 salivary duct carcinomas were positive for CEA. 5 of 8 squamous cell carcinomas and 9 of 21 carcinomas in a pleomorphic adenoma were also positive for CEA.

The anaplastic carcinomas were negative. The distribution pattern of the presence of CEA in the carcinomatous and the adjacent normal or inflamed tissue was analysed. The results are discussed with regard to their histogenetic and diagnostic implications.

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Authors and Affiliations

  1. Institute of Pathology, University of Hamburg and Tumour Center Hamburg, Martinistrasse 52, D-2000, Hamburg 20, Federal Republic of Germany

    J. Caselitz, T. Jaup & G. Seifert

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  1. J. Caselitz
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  2. T. Jaup
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  3. G. Seifert
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Additional information

Prof. Dr. med. Dr. med. h.c. Karl Lennert, Kiel, dedicated on the occasion of his 60th birthday

Supported by Hamburger Stiftung zur Förderung der Krebsbekämpfung and by the Deutsche Forschungsgemeinschaft

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Caselitz, J., Jaup, T. & Seifert, G. Immunohistochemical detection of carcinoembryonic antigen (CEA) in parotid gland carcinomas. Virchows Archiv [Pathol Anat] 394, 49–60 (1981). https://doi.org/10.1007/BF00431664

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