Skip to main content
SpringerLink
Log in

The cytological behavior of a human ring-chromosome

  • Published:
Chromosoma Aims and scope Submit manuscript

Abstract

A ring chromosome derived from group 17–18 was found in a mentally retarded girl. The ring shows considerable variability. With respect to the size the ring is enlarged in 9% of the cells. In 19% of the cells the ring is eliminated; in these cells the chromosome number is only 45. The elimination of the ring has been studied. There are cytological indications of two simultaneous mechanisms: lagging and destruction of complex unstable structures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature

  • Aula, P., U. Gripenberg, L. Hjelt, J. Leisti, J. Palo, B. von Schoultz, and E. Suomalainen: In preparation (1967).

  • Brosseau, G. E.: Some aspects of ring chromosome behavior in Drosophila. Drosophila Information Service 41, 97–99 (1966).

    Google Scholar 

  • Cooke, P., and R. R. Gordon: Cytological studies on a human ring chromosome. Ann. hum. Genet. 29, 147–150 (1965).

    Google Scholar 

  • Grouchy, J. de: Chromosome 18: a topologic approach. J. Pediat. 66, 414–431 (1965).

    Google Scholar 

  • Lindsten, J.: The nature and origin of X-chromosome aberrations in Turner's syndrom. Uppsala: Almqvist & Wicksell 1963.

    Google Scholar 

  • Lucas, M., N. H. Kemp, J. R. Ellis, and R. Marshall: A small autosomal ring chromosome in a female infant with congenital malformations. Ann. hum. Genet. 27, 189–195 (1963).

    Google Scholar 

  • McClintock, B.: The production of homozygous deficient tissues with mutant characteristics by means of the aberrant mitotic behavior of ring-shaped chromosomes. Genetics 23, 315–376 (1938).

    Google Scholar 

  • Nichols, W. W., A. Levan, P. Aula, and E. Norrby: Extreme chromosome breakage induced by measles virus in different in vitro systems. Hereditas (Lund) 51, 380–382 (1964).

    Google Scholar 

  • Saksela, E., P. Aula, and K. Cantell: Chromosomal damage of human cells induced by Sendai virus. Ann. Med. exp. Fenn. 43, 132–136 (1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Genetics, University of Helsinki and the Rinnekoti Institution for Mentally Retarded, Helsinki

    Ulla Gripenberg

Authors
  1. Ulla Gripenberg
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gripenberg, U. The cytological behavior of a human ring-chromosome. Chromosoma 20, 284–289 (1967). https://doi.org/10.1007/BF00326186

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00326186

Keywords

Search

Navigation