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A case of vogt-koyanagi-harada syndrome in a patient affected by hodgkin's disease

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Summary

The Vogt-Koyanagi-Harada (VKH) syndrome, a disease of unknown origin, characterized by inflammation of the uveal tract, retina and meninges, was observed in a patient with Hodgkin's disease (HD) who had been treated with chemotherapy and radiotherapy. Ten years later the patient developed a cluster of neurological symptoms and signs (fever, pain, bilateral hypoacousia, dizziness, uveitis and psychiatric disorder) which were initially interpreted as a relapse of HD. The diagnosis of VKH syndrome was thereafter suspected from the clinical findings, response to therapy and further evolution. During the follow-up (14 months) the patient showed a varying course; hypoacousia remained unaltered while uveitis recurred and only a partial improvement was obtained by immunosuppressive therapy.

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Authors and Affiliations

  1. Department of Haematology, Niguarda Cà Granda Hospital, I-20162, Milan, Italy

    D. Cipriani & G. Landonio

  2. Department of Neurology, Niguarda Cà Granda Hospital, I-20162, Milan, Italy

    C. Canepari

Authors
  1. D. Cipriani
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  2. G. Landonio
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  3. C. Canepari
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Cipriani, D., Landonio, G. & Canepari, C. A case of vogt-koyanagi-harada syndrome in a patient affected by hodgkin's disease. J Neurol 236, 303–304 (1989). https://doi.org/10.1007/BF00314462

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  • DOI: https://doi.org/10.1007/BF00314462

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