Summary
In a data base consisting of 1665 pairs of loci linkage between Inv and Jk is significant \((\hat z = 3.38 {\text{at}} \hat \theta = 0.23)\). Recombination is nearly the same in the two sexes \((\hat \theta _{\text{m}} = 0.21,\hat \theta _{\text{f}} = 0.25)\). The reason why this linkage was not noticed earlier is discussed.
Similar content being viewed by others
References
Chautard-Freire-Maia, E. A.: Linkage relationships between 22 autosomal markers. Ann. Hum. Genet. 38, 191–198 (1974)
Edwards, J. H.: Total lods for linkage analysed by the New York Blood Center and Birmingham computer programs. New Haven Conference (1973): First international workshop on human gene mapping. Birth defects: Original article series, Vol. 10, No. 3, pp. 187–202. New York: The National Foundation 1974
Falk, C. T., Walker, M. E., Martin, M. D., Allen, F. H., Jr.: Autosomal linkage in humans (Methodology and results of computer analysis). Ser. Haemat. 8, 153–237 (1975)
Krieger, H., Morton, N. E., Mi, M. P., Azevedo, E., Freire-Maia, A., Yasuda, N.: Racial admixture in Northeastern Brazil. Ann. Hum. Genet. 29, 113–125 (1965)
Moton, N. E.: The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am. J. Hum. Genet. 8, 80–96 (1956)
Morton, N. E., Krieger, H., Mi, M. P.: Natural selection on polymorphisms in Northeastern Brazil. Am. J. Hum. Benet. 18, 153–171 (1966)
Ott, J., Schrott, H. G., Goldstein, J. L., Hazzard, W. R., Allen, F. H., Jr., Falk, C. T., Motulsky, A. G.: Linkage studies in a large kindred with familial hypercholesterolemia. Am. J. Hum. Benet. 26, 598–603 (1974)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Keats, B.J.B., Morton, N.E. & Rao, D.C. Likely linkage: Inv with Jk. Hum Genet 39, 157–159 (1977). https://doi.org/10.1007/BF00287007
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00287007