Summary
A comparative study was performed on the sex ratio among embryos and newborns in a Russian population (Moscow).
The secondary sex ratio was studied in 81 914 babies born in different regions of Moscow during the period 1962–1971. It was 105.8 boys to 100 girls. Neither maternal age nor month of birth was observed to have any effect on the secondary sex ratio.
The sex chromatin was studied in 3000 embryos obtained from induced abortions. The ratio of male to female embryos was 103.4:100. It dose not differ from either Mendelian segregation (1:1) or the secondary sex ratio in a population studied. It was calculated that more precise determination of the sex ratio in the embryonal period would require the study of not less than 17 500 embryos.
The confidence limits are presented for the significance of possible differences in the sex ratio in samples ranging from 100 to 500000 in size.
Zusammenfassung
In einer russischen Bevölkerung (Moskau) wurde das Geschlechts-verhältnis unter Embryonen und Neugeborenen verglichen.
Das sekundäre Geschlechtsverhältnis (bei Neugeborenen) wurde bei 81 914 in Moskau geborenen Babys für den Zeitraum 1962–1971 untersucht. Ergebnis: 105,8♂ : 100♀. Weder das Alter der Mutter noch die Jahreszeit beeinflußte diesen Wert.
Bei 3000 Embryonen aus induzierten Aborten wurde das Sex-Chromatin bestimmt. Es ergab sich ein Verhältnis 103,4 ♂ : 100 ♀. Es besteht weder ein Unterschied zu dem erwarteten 1:1-Verhältnis noch zu dem sekundären Geschlechtsverhältnis. Für eine genauere Bestimmung wäre eine Stichprobe an mindestens 17 500 Embryonen erforderlich.
Es werden die Vertrauensgrenzen für eine mögliche Änderung des Geschlechtsverhältnisses bei Stichprobengrößen von 100 bis 500000 Beobachtungen angegeben.
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Bochkov, N.P., Kostrova, A.A. Sex ratio among human embryos and newborns in a Russian population. Hum Genet 17, 91–98 (1973). https://doi.org/10.1007/BF00277904
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DOI: https://doi.org/10.1007/BF00277904