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Binding behaviour on DNA-agar of a naturally occurring cross-linked fraction in rodent DNA

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Summary

A naturally occurring, cross-linked fraction, constituting about 1% of the total DNA, has been isolated from the DNA of mice and rats. In sharp contrast to the rest of the rapidly renaturing DNA, this material shows poor binding ability during incubation in agar with DNA of the same species.

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References

  • Alberts, B. M.: Characterization of a naturally occurring, cross-linked fraction of DNA. II. Origin of the cross-linkage. J. molec. Biol. 32, 405–421 (1968).

    Google Scholar 

  • —, and P. Doty: Characterization of a naturally occurring, cross-linked fraction of DNA. I. Nature of the cross-linkage. J. molec. Biol. 32, 379–403 (1968).

    Google Scholar 

  • Blake, R. D., and J. R. Fresco: Polynucleotides. VII. Spectrophotometric study of the kinetics of formation of the two-stranded helical complex resulting from the interaction of polyriboadenylate and polyribouridylate. J. molec. Biol. 19, 145–160 (1960).

    Google Scholar 

  • Britten, R. J., and M. Waring: “Renaturation” of the DNA of higher organisms. Carnegie Inst. Wash. Yearbook 64, 316 (1965).

    Google Scholar 

  • McLaren, A., and P. M. B. Walker: Discriminating power of rodent deoxyribonucleic acid on incubation in agar. Nature (Lond.) 211, 486–490 (1966).

    Google Scholar 

  • —: Correspondence of certain fractions of mouse DNA. Nature (Lond.) 221, 771 (1969).

    Google Scholar 

  • Walker, P. M. B., and A. McLaren: Fractionation of mouse deoxyribonucleic acid on hydroxyapatite. Nature (Lond.) 208, 1175–1179 (1965).

    Google Scholar 

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Authors and Affiliations

  1. Dept. of Zoology, University of Edinburgh, Edinburgh, UK

    P. M. B. Walker

  2. Agricultural Research Council Unit of Animal Genetics, University of Edinburgh, Edinburgh, UK

    Anne McLaren

  3. Institute of Animal Genetics, West Mains Road, 9, Edinburgh, Scotland

    Anne McLaren

Authors
  1. P. M. B. Walker
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  2. Anne McLaren
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Communicated by G. Melchers

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Walker, P.M.B., McLaren, A. Binding behaviour on DNA-agar of a naturally occurring cross-linked fraction in rodent DNA. Molec. Gen. Genet. 104, 104–106 (1969). https://doi.org/10.1007/BF00277366

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  • DOI: https://doi.org/10.1007/BF00277366

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