Abstract
From a collection of objects identified by a common characteristic such as mutations of a given phenotype or DNA sequences with a given property, it is possible to estimate the total number of classes these objects may belong to from the number of such classes represented in the sample. An estimation procedure is presented here complementing earlier work by Lewontin and Prout (1956). The precision and bias of the astimate can also be calculated.
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Engels, W.R. On estimating the total number of genes of a given kind in the genome and similar problems. J. Math. Biology 11, 45–50 (1981). https://doi.org/10.1007/BF00275823
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DOI: https://doi.org/10.1007/BF00275823