Summary
N and I group plasmids, which increase methylmethane sulfonate (MMS) mutagenesis in lexA + strains of E. coli WP2 may be divided into two classes: those restoring part of the mutability of lexA - strains (class I) and those leaving lexA - strains non-mutable (class II). Almost complete restoration of MMS mutability is obtained by class I plasmids in a partially suppressed lexA rnm strain, while class II plasmids cause far fewer MMS revertants in this strain than in lexA +. A pair of class I and II plasmids in lexA - shows a synergistic effect on mutability. These two classes do not coincide with plasmid division into incompatibility groups.
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Babudri, N., Monti-Bragadin, C. Restoration of mutability in non-mutable Escherichia coli carrying different plasmids. Molec. Gen. Genet. 155, 287–290 (1977). https://doi.org/10.1007/BF00272807
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DOI: https://doi.org/10.1007/BF00272807