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Altered tetracycline resistance in pSC101 recombinant plasmids

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Summary

Investigation of tetracycline resistance genetically determined by the plasmid pSC101 and several recombinants of pSC101 containing of EcoRI generated DNA fragments inserted at the EcoRI site has revealed significant differences in the phenotypic expression of that resistance. The altered phenotypes of the recombinant plasmids may be the result of the location of the EcoRI site of pSC101, which has been determined to be near the genetic elements involved with tetracycline resistance.

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Authors and Affiliations

  1. Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, San Francisco, California, USA

    Robert C. Tait, Raymond L. Rodriguez & Herbert W. Boyer

Authors
  1. Robert C. Tait
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  2. Raymond L. Rodriguez
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  3. Herbert W. Boyer
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Communicated by W. Gilbert

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Tait, R.C., Rodriguez, R.L. & Boyer, H.W. Altered tetracycline resistance in pSC101 recombinant plasmids. Molec. Gen. Genet. 151, 327–331 (1977). https://doi.org/10.1007/BF00268797

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  • DOI: https://doi.org/10.1007/BF00268797

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