Summary
The activity of retinal ganglion cells and cortical cells with overlapping receptive fields was simultaneously recorded. The responses to moving stimuli of individual simple cortical cells could be accounted for on the basis of the cell receiving either on-centre or off-centre afferents; instances in which it was necessary to postulate a mixed on- and off-centre input were not found. In six instances cross correlograms of ganglion cell and cortical cell activity showed that the ganglion cell was afferent, via a relay cell in the LGN, to the cortical neurone. The receptive fields of such pairs were almost completely overlapping and concentric. In three cases a sustained ganglion cell projected to a simple cortical cell. In one case a transient ganglion cell projected to a simple cell, and in one case a sustained and a transient ganglion cell projected to the same simple cell.
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Bishop, P.O., Coombs, J.S., Henry, G.H.: Responses to visual contours: spatio-temporal aspects of excitation in the receptive fields of simple striate neurones. J. Physiol. (Lond.) 219, 625–658 (1971a)
Bishop, P.O., Coombs, J.S., Henry, G.H.: Interaction effects of visual contours on the discharge frequency of simple striate neurones. J. Physiol. (Lond.) 219, 659–688 (1971b)
Bishop, P.O., Coombs, J.S., Henry, G.H.: Receptive fields of simple cells in cat striate cortex. J. Physiol. (Lond.) 231, 31–60 (1973)
Cleland, B.G., Dubin, R.W., Levick, W.R.: Sustained and transient neurones in the cat's retina and lateral geniculate nucleus. J. Physiol. (Lond.) 217, 473–496 (1971a)
Cleland, B.G., Dubin, R.W., Levick, W.R.: Simultaneous recording of input and output of lateral geniculate neurones. Nature (New Biol.) 231, 191–192 (1971b)
Cleland, B.G., Levick, W.R., Sanderson, K.J.: Properties of sustained and transient ganglion cells in the cat retina. J. Physiol. (Lond.) 228, 649–680 (1973)
Creutzfeldt, O.D., Innocenti, G.M., Brooks, D.: Vertical organisation in the visual cortex (area 17) of the cat. Exp. Brain Res. 21, 315–336 (1974)
Creutzfeldt, O.D., Ito, M.: Functional synaptic organisation of primary visual cortex neurones in the cat. Exp. Brain Res. 6, 324–352 (1968)
Creutzfeldt, O.D., Kuhnt, U., Benevento, L.A.: An intracellular analysis of visual cortical responses to moving stimuli: responses in a co-operative neuronal network. Exp. Brain Res. 21, 251–274 (1974)
Dreher, B., Sanderson, K.J.: Receptive field analysis: responses to moving contours by single lateral geniculate neurones in the cat. J. Physiol. (Lond.) 234, 95–118 (1973)
Dubin, M.W., Cleland, B.G.: The organisation of visual inputs to interneurones of the lateral geniculate nucleus of the cat. J. Neurophysiol. 40, 410–427 (1977)
Fernald, R., Chase, R.: An improved method for plotting retinal landmarks and focussing the eyes. Vision Res. 11, 95–96 (1971)
Hoffmann, K.-P., Stone, J.: Conduction velocity of afferents to cat visual cortex: a correlation with cortical receptive field properties. Brain Res. 32, 460–466 (1971)
Hubel, D.H., Wiesel, T.N.: Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. J. Physiol. (Lond.) 160, 106–154 (1962)
Ikeda, H., Wright, M.J.: Evidence for ‘sustained’ and ‘transient’ neurones in the cat's visual cortex. Vision Res. 14, 133–136 (1974)
Ikeda, H., Wright, M.J.: The relationship between the sustained/transient and simple/complex classification of neurones in area 17 of the cat. J. Physiol. (Lond.) 244, 59P (1975a)
Ikeda, H., Wright, M.J.: Retinotopic distribution, visual latency and orientation tuning of sustained and transient cortical neurones in area 17 of the cat. Exp. Brain Res. 22, 384–397 (1975b)
Ikeda, H., Wright, M.J.: Spatial and temporal properties of sustained and transient neurones in area 17 of the cat. Exp. Brain Res. 26, 363–383 (1975c)
Lee, B.B., Virsu, V., Creutzfeldt, O.D.: Responses of cells in the cat lateral geniculate nucleus to moving stimuli at various levels of light and dark adaptation. Exp. Brain Res. 27, 51–59 (1977)
Levick, W.R.: Another tungsten micro-electrode. Med. biol. Engng. 10, 510–515 (1972)
Levick, W.R., Cleland, B.G., Dubin, M.W.: Lateral geniculate neurones of the cat: retinal inputs and physiology. Invest. Ophthal. 11, 302–311 (1972)
Movshon, J.A.: The velocity tuning of single units in cat striate cortex. J. Physiol. (Lond.) 249, 445–468 (1975)
Pettigrew, J.D., Nikara, T., Bishop, P.O.: Responses to moving slits by single units in cat striate cortex. Exp. Brain Res. 6, 373–390 (1968)
Rodieck, R.W.: Maintained activity of cat retinal ganglion cells. J. Neurophysiol. 30, 1043–1071 (1967)
Sherman, S.M., Watkins, D.W., Wilson, J.R.: Further difference in receptive field properties of simple and complex cells in cat striate cortex. Vision Res. 9, 919–928 (1976)
Singer, W., Tretter, F., Cynader, M.: Organisation of cat striate cortex; a correlation of receptive field properties with afferent and efferent connections. J. Neurophysiol. 38, 1080–1098 (1975)
Wilson, J.R., Sherman, S.M.: Receptive field characteristics of neurons in cat striate cortex: changes with visual field eccentricity. J. Neurophysiol. 39, 512–533 (1976)
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On leave from the Department of Physiology, John Curtin School of Medical Research, Australian National University, P.O. B. 334, Canberra City ACT 2601, Australia
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Lee, B.B., Cleland, B.G. & Creutzfeldt, O.D. The retinal input to cells in area 17 of the cat's cortex. Exp Brain Res 30, 527–538 (1977). https://doi.org/10.1007/BF00237642
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DOI: https://doi.org/10.1007/BF00237642