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Perchlorate and Diet: Human Exposures, Risks, and Mitigation Strategies

  • Food, Health, and the Environment (KE Nachman, Section Editor)
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Abstract

Perchlorate is an endocrine-disrupting chemical that interferes with the normal functioning of the thyroid gland. Maternal thyroid dysfunction during gestation may alter fetal brain development. Perchlorate contamination is widespread: it is present in the body of all Americans tested and the majority of foods tested. The main sources of food contamination appear to be hypochlorite bleach, a disinfectant and sanitizer, that when poorly managed quickly degrades to perchlorate and perchlorate-laden plastic food packaging for dry food or localized contamination from manufacturing or processing of the chemical. Eliminating perchlorate from food packaging and improving bleach management, such as reducing concentration and storage time and temperature, would result in reduced perchlorate contamination of food and water.

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Correspondence to Maricel V. Maffini.

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Conflict of Interest

Maricel V. Maffini is coauthor of the food additive petition pending before the US Food and Drug Administration requesting that the agency remove its approval of the use of perchlorate in food contact substances.

Thomas G. Neltner is a coordinator and coauthor of the food additive petition pending before the US Food and Drug Administration requesting that the agency remove its approval of the use of perchlorate in food contact substances.

Leonardo Trasande declares he has no conflict of interest.

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Maffini, M.V., Trasande, L. & Neltner, T.G. Perchlorate and Diet: Human Exposures, Risks, and Mitigation Strategies. Curr Envir Health Rpt 3, 107–117 (2016). https://doi.org/10.1007/s40572-016-0090-3

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