Infection

, Volume 40, Issue 4, pp 441–443

Fatal dengue hemorrhagic fever imported into Germany

Authors

    • Department of Virology, Clinical Virology LaboratoryBernhard Nocht Institute for Tropical Medicine
  • K. Tenner-Racz
    • Department of PathologyBernhard Nocht Institute for Tropical Medicine
  • D. Poppert
    • Academy for Psychosomatic Medicine and Psychotherapy
  • P. Emmerich
    • Department of Virology, Clinical Virology LaboratoryBernhard Nocht Institute for Tropical Medicine
  • C. Frank
    • Robert Koch Institute
  • C. Dinges
    • Department of Forensic MedicineUniversity of Munich
  • R. Penning
    • Department of Forensic MedicineUniversity of Munich
  • A. Nerlich
    • Department of PathologyKlinikum Bogenhausen
  • P. Racz
    • Department of PathologyBernhard Nocht Institute for Tropical Medicine
  • S. Günther
    • Department of Virology, Clinical Virology LaboratoryBernhard Nocht Institute for Tropical Medicine
Case Report

DOI: 10.1007/s15010-011-0208-3

Cite this article as:
Schmidt-Chanasit, J., Tenner-Racz, K., Poppert, D. et al. Infection (2012) 40: 441. doi:10.1007/s15010-011-0208-3

Abstract

Dengue virus (DENV) is an arthropod-borne virus (family Flaviviridae) causing dengue fever or dengue hemorrhagic fever. Here, we report the first fatal DENV infection imported into Germany. A female traveler was hospitalized with fever and abdominal pain after returning from Ecuador. Due to a suspected acute acalculous cholecystitis, cholecystectomy was performed. After cholecystectomy, severe spontaneous bleeding from the abdominal wound occurred and the patient died. Postmortem analysis of transudate and tissue demonstrated a DENV secondary infection of the patient and a gallbladder wall thickening (GBWT) due to an extensive edema.

Keywords

Dengue virusGermanyDengue hemorrhagic feverImmunohistochemistry

Copyright information

© Springer-Verlag 2011