Infection

, Volume 40, Issue 4, pp 441–443

Fatal dengue hemorrhagic fever imported into Germany

  • J. Schmidt-Chanasit
  • K. Tenner-Racz
  • D. Poppert
  • P. Emmerich
  • C. Frank
  • C. Dinges
  • R. Penning
  • A. Nerlich
  • P. Racz
  • S. Günther
Case Report

DOI: 10.1007/s15010-011-0208-3

Cite this article as:
Schmidt-Chanasit, J., Tenner-Racz, K., Poppert, D. et al. Infection (2012) 40: 441. doi:10.1007/s15010-011-0208-3

Abstract

Dengue virus (DENV) is an arthropod-borne virus (family Flaviviridae) causing dengue fever or dengue hemorrhagic fever. Here, we report the first fatal DENV infection imported into Germany. A female traveler was hospitalized with fever and abdominal pain after returning from Ecuador. Due to a suspected acute acalculous cholecystitis, cholecystectomy was performed. After cholecystectomy, severe spontaneous bleeding from the abdominal wound occurred and the patient died. Postmortem analysis of transudate and tissue demonstrated a DENV secondary infection of the patient and a gallbladder wall thickening (GBWT) due to an extensive edema.

Keywords

Dengue virusGermanyDengue hemorrhagic feverImmunohistochemistry

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • J. Schmidt-Chanasit
    • 1
  • K. Tenner-Racz
    • 2
  • D. Poppert
    • 3
  • P. Emmerich
    • 1
  • C. Frank
    • 4
  • C. Dinges
    • 5
  • R. Penning
    • 5
  • A. Nerlich
    • 6
  • P. Racz
    • 2
  • S. Günther
    • 1
  1. 1.Department of Virology, Clinical Virology LaboratoryBernhard Nocht Institute for Tropical MedicineHamburgGermany
  2. 2.Department of PathologyBernhard Nocht Institute for Tropical MedicineHamburgGermany
  3. 3.Academy for Psychosomatic Medicine and PsychotherapyMunichGermany
  4. 4.Robert Koch InstituteBerlinGermany
  5. 5.Department of Forensic MedicineUniversity of MunichMunichGermany
  6. 6.Department of PathologyKlinikum BogenhausenMunichGermany