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Evaluation of anti-inflammatory, analgesic, antipyretic and antiulcer activity of Punarnavasava: an Ayurvedic formulation of Boerhavia diffusa

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Abstract

Punarnavasava, an Ayurvedic liquid dosage form containing self generated alcohol is commonly used to treat inflammatory conditions and edema. In the present study, we evaluated anti-inflammatory, analgesic, antipyretic, and antiulcer activity of three different brands of Punarnavasava. The formulation significantly inhibited carrageenan-induced rat paw edema, cotton pellet-induced granuloma, formalin-induced paw licking, yeast induced hyperpyrexia and pyloric ligated ulcers in rats. The study concludes that Punarnavasava has anti-inflammatory, central as well as peripheral antinociceptive, antipyretic and antiulcer activity and thus justifies its use in inflammatory conditions.

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Authors and Affiliations

  1. MGV’s Pharmacy College, Panchavati, Nasik, 422 003, India

    Manisha Gharate

  2. Pinnacle Biomedical Institute of Research and Education, Bhopal, India

    Veena Kasture

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  1. Manisha Gharate
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  2. Veena Kasture
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Correspondence to Manisha Gharate.

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Gharate, M., Kasture, V. Evaluation of anti-inflammatory, analgesic, antipyretic and antiulcer activity of Punarnavasava: an Ayurvedic formulation of Boerhavia diffusa . Orient Pharm Exp Med 13, 121–126 (2013). https://doi.org/10.1007/s13596-012-0081-3

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  • DOI: https://doi.org/10.1007/s13596-012-0081-3

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