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Cryptogenic cirrhosis is the leading cause for listing for liver transplantation in Sri Lanka

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Abstract

Hepatitis B and C are rare in Sri Lanka. Nonalcoholic fatty liver disease is increasing in the country. Eighty-one patients referred for liver transplantation (LT) over a period of 18 months were prospectively evaluated. Ninety-two percent (n = 74) were males. Cryptogenic cirrhosis was the leading indication for LT (58 %, n = 47) followed by alcohol in 27 % (n = 33). Hepatitis B and C were not seen in our cases. The liver biochemistry and clinical status of cirrhosis were similar in cryptogenic and alcoholic cirrhotics. Fourteen patients died while waiting for transplant, and nine transplants were performed. Cryptogenic cirrhosis is the leading cause for LT in Sri Lanka.

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References

  1. Chitturi S, Farrell GC, George J. Non-alcoholic steatohepatitis in the Asia-Pacific region: future shock? J Gastroenterol Hepatol. 2004;19:368–74.

    Article  PubMed  Google Scholar 

  2. Yoon K-H, Lee J-H, Kim J-W, et al. Epidemic obesity and type 2 diabetes in Asia. Lancet. 2006;368:1681–8.

    Article  PubMed  Google Scholar 

  3. Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology. 1990;11:74–80.

    Article  PubMed  Google Scholar 

  4. Liou I, Kowdley KV. Natural history of nonalcoholic steatohepatitis. J Clin Gastroenterol. 2006;40 Suppl 1:S11–6.

    PubMed  Google Scholar 

  5. Koehler E, Watt K, Charlton M. Fatty liver and liver transplantation. Clin Liver Dis. 2009;13:621–30.

    Article  PubMed  Google Scholar 

  6. Dassanayake AS, Kasturiratne A, Rajindrajith S, et al. Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan population. J Gastroenterol Hepatol. 2009;24:1284–8.

    Article  PubMed  Google Scholar 

  7. Pinidiyapathirage MJ, Dassanayake AS, Rajindrajith S, et al. Non-alcoholic fatty liver disease in a rural, physically active, low income population in Sri Lanka. BMC Res Notes. 2011;4:513.

    Article  PubMed  Google Scholar 

  8. Fan J-G, Saibara T, Chitturi S, et al. What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific? J Gastroenterol Hepatol. 2007;22:794–800.

    Article  PubMed  Google Scholar 

  9. Misra A, Misra R, Wijesuriya M, Banerjee D. The metabolic syndrome in South Asians: continuing escalation and possible solutions. Indian J Med Res. 2007;125:345–54.

    PubMed  Google Scholar 

  10. Mohan V, Farooq S, Deepa M, Ravikumar R, Pitchumoni CS. Prevalence of non-alcoholic fatty liver disease in urban south Indians in relation to different grades of glucose intolerance and metabolic syndrome. Diabetes Res Clin Pract. 2009;84:84–91.

    Article  PubMed  CAS  Google Scholar 

  11. Maheshwari A, Thuluvath PJ. Cryptogenic cirrhosis and NAFLD: are they related? Am J Gastroenterol. 2006;101:664–8.

    Article  PubMed  Google Scholar 

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Correspondence to R. C. Siriwardana.

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Siriwardana, R.C., Niriella, M.A., Liyanage, C.A.H. et al. Cryptogenic cirrhosis is the leading cause for listing for liver transplantation in Sri Lanka. Indian J Gastroenterol 32, 397–399 (2013). https://doi.org/10.1007/s12664-013-0376-4

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  • DOI: https://doi.org/10.1007/s12664-013-0376-4

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