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Nomenclature of ISCRl elements capable of mobilizing antibiotic resistance genes present in complex class 1 integrons

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Abstract

The dissemination of many antibiotic resistance genes has arisen among members of the family Enterobacteriaceae. The dissemination mechanism of these antibiotic resistance genes is closely linked with insertion sequence common region 1 (ISCRl). Thus, caution must be taken in clinical settings to prevent further dissemination of these antibiotic resistance genes. A nomenclature system of ISCRl variants, important for the antibiotic resistance dissemination, was proposed. The proposed system can designate all ISCRl variants on the basis of the detection time and by considering amino-acid substitution(s) compared with ISCRla. This nomenclature system of ISCRl variants can be applied to 19 groups (ISCRl to ISCR19) of the ISCR family and help some researchers to correctly designate new ISCR subgroups.

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Authors and Affiliations

  1. Drug Resistance Proteomics Laboratory, Department of Biological Sciences, Myongji University, Gyeonggido, 449-728, Republic of Korea

    Seung Ghyu Sohn, Jae Jin Lee, Jae Seok Song, Jung Hun Lee, Ha Ik Sun, Kwang Seung Park, Byeong Chul Jeong & Sang Hee Lee

  2. Research Institute for Antimicrobial Resistance, Kosin University College of Medicine, Busan, 602-030, Republic of Korea

    II Kwon Bae

  3. Korea Ocean Research and Development Institute, Marine Biotechnology Research Center, Ansan, 425-600, Republic of Korea

    Jung Hun Lee & Jung-Hyun Lee

Authors
  1. Seung Ghyu Sohn
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  2. Jae Jin Lee
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  3. Jae Seok Song
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  4. Jung Hun Lee
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  5. Ha Ik Sun
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  6. Kwang Seung Park
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  7. II Kwon Bae
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  8. Jung-Hyun Lee
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  9. Byeong Chul Jeong
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  10. Sang Hee Lee
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Correspondence to Sang Hee Lee.

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These authors contributed equally to this work.

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Sohn, S.G., Lee, J.J., Song, J.S. et al. Nomenclature of ISCRl elements capable of mobilizing antibiotic resistance genes present in complex class 1 integrons. J Microbiol. 47, 514–516 (2009). https://doi.org/10.1007/s12275-009-0054-5

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  • DOI: https://doi.org/10.1007/s12275-009-0054-5

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