References
Fukuda J.; Okamura K.; Ishihara K.; Mizumoto M.; Nakazawa K.; Ijima H.; Kajiwara T.; Funatsu K. Differentiation effects by the combination of spheroid formation and sodium butyrate treatment in human hepatoblastoma cell line (HepG2): a possible cell source for hybrid artificial liver. Cell Transplant 14: 819–827; 2005.
Itoh M.; Abe Y.; Iwama Y.; Kimura F.; Satoh M.; Shoji M.; Takahashi J.; Toshima G.; Sasaki H.; Hiwatashi K.; Hata K. HPLC analysis of lipoproteins in culture medium of hepatoma cells: an in vitro system for screening antihyperlipidemic drugs. Biotechnol Lett 31: 953–957; 2009.
Takahashi J.; Toshima G.; Matsumoto Y.; Kimura F.; Kiuchi T.; Hamada K.; Hata K. In vitro screening for antihyperlipidemic activities in foodstuffs by evaluating lipoprotein profiles secreted from human hepatoma cells. J Nat Med 65: 670–674; 2011.
Wang X. M.; Wang X.; Ling B. S. J.; Evers B. M. Effect of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. Ann Surg 214: 922–931; 1998.
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Takahashi, J., Kimura, F., Miura, M. et al. Advantages of assessing lipoprotein profiles in hepatic cell differentiation. In Vitro Cell.Dev.Biol.-Animal 49, 554–556 (2013). https://doi.org/10.1007/s11626-013-9639-8
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DOI: https://doi.org/10.1007/s11626-013-9639-8