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The effects of progesterone treatment following artificial insemination on the reproductive performance of dairy cows

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Abstract

The objective of this study was to examine the effects of increasing circulating progesterone in multiparous Holstein cows, using an intravaginal progesterone implant between days 3 and 7 following fixed-time artificial insemination (FTAI). The animals were randomly assigned into two groups: (1) treatment group and (2) control (no treatment). The experiment took place during periods of high and mild temperatures. Pregnancy rates were evaluated by ultrasound at 30 and 60 days after FTAI; embryonic and fetal mortality rates were also evaluated on these dates. The temperature and humidity index on the day of FTAI were different (P < 0.05) during the times of interest, but it did not affect conception rates. Neither the conception rates at days 30 and 60 nor the embryonic and fetal mortality rates differed between the groups during either the high- or mild-temperature periods (P > 0.05). Throughout the experimental period, the serum progesterone concentration was higher in the treatment group than in the control (P < 0.05). We conclude that the intravaginal progesterone implant inserted from days 3 to 7 following FTAI had no effect on conception rates at days 30 and 60 or on embryonic or fetal mortality rates but enhances the serum progesterone concentrations following treatment in multiparous Holstein cows during high- and mild-temperature periods.

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References

  • Arndt, W.J., Holle, A.J., Bauer, M.L., Kirsch, J.D., Schimek, D.E., Odde, K.G. and Vonnahme, K.A., 2009. Effect of post-insemination progesterone supplementation on pregnancy rate in dairy cows, The Canadian Journal of Veterinary Research, 73 (4), 271-274

    CAS  Google Scholar 

  • Baumgard, L. and Rhoads, R., 2012. Efeito do estresse calórico no metabolismo e na produção de leite e estratégias para minimizar efeitos negativos. XVI Curso Novos Enfoques na Produção e Reprodução de Bovinos, Uberlândia, MG Brasil. Available at <http://www.fca.unesp.br/conapecjr>. Accessed 22 March 2012

  • Bó, G.A., Cutaia, L., Peres, L.C., Pincinato, D., Maraña, D. and Baruselli, P.S., 2007. Technologies for fixed-time artificial insemination and their influence on reproductive performance of Bos indicus cattle, Society of Reproduction and Fertility (suppl.), 64, S223-S236

    Google Scholar 

  • Carter, F., Rings, F., Mamo, S., Holker, M., Kuzmany, A., Besenfelder, U., Havlicek, V., Mehta, J.P., Tesfaye, D., Schellander, K. and Lonergan, P., 2010. Effect of elevated circulating progesterone concentration on bovine blastocyst development and global transcriptome following endoscopic transfer of in vitro produced embryos to the bovine oviduct, Biology of Reproduction, 83 (5), 707-719

    Article  CAS  PubMed  Google Scholar 

  • Ealy, A.D., Drost, M. and Hansen, P.J., 1993. Developmental changes in embryonic resistance to adverse effects of maternal heat stress in cows, Journal of Dairy Science, 76 (10), 2899-2905

    Article  CAS  PubMed  Google Scholar 

  • Ferguson, J. D., Galligan, D. T. and Thomsen, N., 1994. Principal descriptors of body condition score in Holstein cows, Journal of Dairy Science, 77, 2695-2703

    Article  CAS  PubMed  Google Scholar 

  • Forde, N., Carter, F., Fair, T., Crowe, M.A., Evans, A.C.O., Spencer, T.E., Bazer, F.W., McBride, R., Boland, M.P., O'Gaora, P., Lonergan, P. and Roche, J.F., 2009. Progesterone-regulated changes in endometrial gene expression contribute to advanced conceptus development in cattle, Biology of Reproduction, 81, 784-794

    Article  CAS  PubMed  Google Scholar 

  • Garcia-Ispierto, I. and López-Gatius, F., 2012. Effects of GnRH or progesterone treatment on day 5 post-AI on plasma progesterone, luteal blood flow and leucocyte counts during the luteal phase in dairy cows, Reproduction in Domestic Animals, 47, 224-229

    Article  CAS  PubMed  Google Scholar 

  • Green, M.P., Hunter, M.G. and Mann, G.E., 2005. Relationships between maternal hormone secretion and embryo development on day 5 of pregnancy in dairy cows. Animal Reproduction Science, 88, 179-189

    Article  CAS  PubMed  Google Scholar 

  • Hansen, P.J. and Arechiga, C.F., 1999. Strategies for managing reproduction in the heat-stressed dairy cow, Journal of Animal Science, 77 (suppl. 2), 36-50

    CAS  PubMed  Google Scholar 

  • Mann, G.E. and Lamming, G.E., 1999. The influence of progesterone during early pregnancy in cattle, Reproduction in Domestic Animals, 34, 269-274

    Article  CAS  Google Scholar 

  • Mann, G.E. and Lamming, G.E., 2001. Relationship between maternal endocrine environment, early embryo development and inhibition of the luteolytic mechanism in cows, Reproduction, 121, 175-180

    Article  CAS  PubMed  Google Scholar 

  • Mann, G.E., Fray, M.D. and Lamming, G.E., 2006. Effects of time of progesterone supplementation on embryo development and interferon-τ production in the cow, The Veterinary Journal, 171 (3), 500-503

    Article  CAS  PubMed  Google Scholar 

  • Maturana Filho, M., Kehrle, A., Scolari, S.C., Miguez, P.H.P., Oliveira, B.M.M. and Madureira, E.H., 2011. Avaliação e comparação dos efeitos do estresse calórico sobre a eficiência reprodutiva de vacas e novilhas nelore durante a estação de monta. In: 48th Reunião Anual da Sociedade Brasileira de Zootecnia, Belém PA, Brasil, 2011 (Sociedade Brasileira de Zootecnia, Brasília), 1-3

  • Mehni, S.B., Shabankareh, H.K., Kazemi-Bonchenari, M. and Eghbali, M., 2012. The comparison of treating Holstein dairy cows with progesterone, CIDR and GnRH after insemination on serum progesterone and pregnancy rates, Reproduction in Domestic Animals, 47 (1), 131-134

    Article  CAS  PubMed  Google Scholar 

  • Neves, J.P., Oliveira, J.F.C., Freitas, V.J.F., Simplício, A.A., Teixeira, D.I.A. and Almeida, J.L., 2008. Diagnóstico de prenhez em ruminantes. In: Biotécnicas aplicadas à reprodução animal, (Varela Editora e Livraria Ltda, São Paulo)

  • Palhano, H. B., 2008. Reprodução em bovinos: fisiopatologia, terapêutica e biotecnologia (LF Livros de Veterinária, Rio de Janeiro)

    Google Scholar 

  • Pandey, A.K., Dhaliwal, G.S., Ghuman, S.S., Singh, J., Kumar, A. and Agarwal, S.K., 2012. Impact of norgestomet supplementation during early luteal phase on subsequent luteal profiles and conception rate in buffalo: a preliminary study, Tropical Animal Health and Production, 45, 293-298

    Article  PubMed  Google Scholar 

  • Ranieri, A.A., Rodrigues, C.A., Vieira, L.M., Silva, P.R.L.S., Gouvea, G.B., Teixeira, A.L.A., Maio, J.R.G., Sales, J.N.S. and Baruselli, P.S., 2011. Comparação da taxa de prenhez de vacas holandesas de alta produção sincronizadas para IATF com protocolo a base de progesterona e estradiol ou duplo ovsynch. In: XXV Reunião Anual da Sociedade Brasileira de Teconologia de Embriões, Cumbuco, PR Brasil, 2011, 383

  • Ravagnolo, O. and Misztal, I., 2002. Effect of heat stress on nonreturn rate in Holsteins: fixed-model analyses, Journal of Dairy Science, 85, 3101-3106

    Article  CAS  PubMed  Google Scholar 

  • Robinson, R.S., Hammond, A.J., Hunter, M.G. and Mann, G.E., 2005. The induction of a delayed post-ovulatory progesterone rise in dairy cows: a novel model, Domestic Animal Endocrinology, 28 (3), 285-295

    Article  CAS  PubMed  Google Scholar 

  • Sangsritavong, S., Combs, D.K., Sartori, R., Armentano, L.E. and Wiltbank, M.C., 2002. High feed intake increases liver blood flow and metabolism of progesterone and estradiol-17β in dairy cattle, Journal of Dairy Science, 85, 2831-2842

    Article  CAS  PubMed  Google Scholar 

  • Sartori, R., Sartor-Bergfelt, R., Mertens, S.A., Guenther, J.N., Parrish, J.J. and Wiltbank, M.C., 2002. Fertilization and early embryonic development in heifers and lactating cows in summer and lactating and dry cows in winter, Journal of Dairy Science, 85 (11), 2803-2812

    Article  CAS  PubMed  Google Scholar 

  • SAS 2000. User's Guide: statistics, 5th ed. (SAS Institute, Cary)

    Google Scholar 

  • Satterfield, M.C., Bazer, F.W. and Spencer, T.E., 2006. Progesterone regulation of preimplantation conceptus growth and galectin 15 (LGALS15) in the ovine uterus, Biology of Reproduction, 75, 289-296

    Article  CAS  PubMed  Google Scholar 

  • Smith, J.F., Harner, J.P., Bradford, B.J. and Collier, R.J., 2012. Estratégias de resfriamento de vacas de leite utilizadas nos EUA. XVI Curso Novos Enfoques na Produção e Reprodução de Bovinos, Uberlândia, MG Brasil. Available at <http://www.fca.unesp.br/conapecjr>. Accessed 22 March 2012

  • Starbuck, G.R. and Mann, G.E., 2010. Differential effects of exogenous progesterone administration at different stages of the luteal phase on endogenous oestradiol concentration in cows, Reproduction in Domestic Animals, 45, 283-286

    Article  CAS  PubMed  Google Scholar 

  • Stronge, A.J., Sreenan, J.M., Diskin, M.G., Mee, J.F., Kenny, D.A. and Morris, D.G., 2005. Post-insemination milk progesterone concentration and embryo survival in dairy cows, Theriogenology, 64, 1212-1224

    Article  CAS  PubMed  Google Scholar 

  • Villa-Mancera, A., Méndez-Mendoza, M., Huerta-Crispín, R., Vázquez-Flores, F. and Córdova-Izquierdo, A., 2011. Effect of climate factors on conception rate of lactating dairy cows in Mexico, Tropical Animal Health and Production, 43 (3), 597-601

    Article  PubMed  Google Scholar 

  • Villarroel, A., Martino, A., BonDurant, R.H., Dèletang, F. and Sischo, W.M., 2004. Effect of post-insemination supplementation with PRID on pregnancy in repeat-breeder Holstein cows, Theriogenology, 61 (7-8), 1513-1520

    Article  CAS  PubMed  Google Scholar 

  • Wheelock, J.B., Rhoads, R.P., VanBaale, M.J., Sanders, S.R. and Baumgard, L.H., 2010. Effects of heat stress energetic metabolism in lactating Holstein cows, Journal of Dairy Science, 93 (2), 644-655

    Article  CAS  PubMed  Google Scholar 

  • Wolfenson, D., Sonego, H., Bloch, A., Shaham-Albalancy, A., Kaim, M., Folman, Y. and Meidan, R., 2002. Seasonal differences in progesterone production by luteinized bovine thecal and granulosa cells. Domestic Animal Endocrinology, 22 (2), 81-90

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

Special thanks are given to the Instituto Federal de Educação, Ciência e Tecnologia Goiano, employees and business partners on the project.

Authors' contributions

All the authors contributed equally to the manuscript.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Instituto Federal de Educação, Ciência e Tecnologia Goiano-Rio Verde Campus, Rio Verde, Goiás, Brazil

    Thaisa Campos Marques & Karen Martins Leão

  2. Universidade Federal de Goiás-Jatai Campus, Jatai, Goiás, Brazil

    Marco Antônio de Oliveira Viu

  3. Department of Animal Science, Universidade de São Paulo, Piracicaba, São Paulo, Brazil

    Roberto Sartori

  4. Rua Costa Gomes no. 1617, Apt. 103, Jardim Goiás, Rio Verde, Goiás, Brazil

    Thaisa Campos Marques

Authors
  1. Thaisa Campos Marques
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  2. Karen Martins Leão
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  3. Marco Antônio de Oliveira Viu
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  4. Roberto Sartori
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Correspondence to Thaisa Campos Marques.

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Marques, T.C., Leão, K.M., de Oliveira Viu, M.A. et al. The effects of progesterone treatment following artificial insemination on the reproductive performance of dairy cows. Trop Anim Health Prod 46, 405–410 (2014). https://doi.org/10.1007/s11250-013-0504-2

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