Feasibility, reliability, and validity of the EQ-5D-Y: results from a multinational study
To examine the feasibility, reliability, and validity of the newly developed EQ-5D-Y.
The EQ-5D-Y was administered in population samples of children and adolescents in Germany, Italy, South Africa, Spain, and Sweden. Percentages of missing values and reported problems were calculated. Test–retest reliability was determined. Spearman’s rank correlation coefficients with other generic measures of HRQOL were calculated. Known groups’ validity was examined by comparing groups with a priori expected differences in HRQOL.
Between 91 and 100% of the respondents provided valid scorings. Sweden had the lowest proportion of reported problems (1–24.9% across EQ-5D-Y dimensions), with the highest proportions in South Africa (2.8–47.3%) and Italy (4.3–39.0%). Percentages of agreement in test–retest reliability ranged between 69.8 and 99.7% in the EQ-5D-Y dimensions; Kappa coefficients were up to 0.67. Correlation coefficients with other measures of self-rated health indicated convergent validity (up to r = −0.56). Differences between groups classified according to presence of chronic conditions, self-rated overall health and psychological problems provided preliminary evidence of known groups’ validity.
Results provide preliminary evidence of the instrument’s feasibility, reliability and validity. Further study is required in clinical samples and for possible future applications in economic analyses.
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Quality of Life Research
Volume 19, Issue 6 , pp 887-897
- Cover Date
- Print ISSN
- Online ISSN
- Springer Netherlands
- Additional Links
- Child health
- Adolescent health
- Industry Sectors
- Ulrike Ravens-Sieberer (1)
- Nora Wille (1)
- Xavier Badia (2)
- Gouke Bonsel (3)
- Kristina Burström (4) (5)
- Gulia Cavrini (6)
- Nancy Devlin (7)
- Ann-Charlotte Egmar (8)
- Narcis Gusi (9)
- Michael Herdman (10) (11)
- Jennifer Jelsma (12)
- Paul Kind (13)
- Pedro R. Olivares (9)
- Luciana Scalone (14) (15)
- Wolfgang Greiner (16)
- Author Affiliations
- 1. Department of Psychosomatics in Children and Adolescents, Research Unit Child Public Health, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany
- 2. Health Economics and Outcomes Research, IMS Health, Doctor Ferran 25-27, 2, 08034, Barcelona, Spain
- 3. Institute of Health Policy and Management, and Department of Prenatal Medicine and Obstetrics (Location Woudenstein, L3-060), Erasmus Medical Centre, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands
- 4. Department of Learning, Informatics, Management and Ethics, Medical Management Centre, Karolinska Institutet, Nobels väg 15a, 171 77, Stockholm, Sweden
- 5. Department of Public Health Sciences, Division of Social Medicine, Karolinska Institutet, Nobels väg 15a, 171 77, Stockholm, Sweden
- 6. Department of Statistics, University of Bologna, Via delle Belle Arti 41, 40126, Bologna, Italy
- 7. Office of Health Economics and Senior Associate, King’s Fund, 12 Whitehall, London, SW1A2DY, UK
- 8. The Red Cross University College, Box 55676, 102 15, Stockholm, Sweden
- 9. Faculty of Sport Sciences, University of Extremadura, Avda Universidad, 10071, Caceres, Spain
- 10. CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
- 11. IMIM-Hospital del Mar, Unitat de Recerca en Serveis Sanitaris, Parc de Recerca Biomedica de Barcelona, Health Services Research Unit, Doctor Aiguader, 88, 08003, Barcelona, Spain
- 12. School of Health and Rehabilitation Sciences, Division of Physiotherapy, University of Cape Town, Anzio Road Observatory, 7925, Cape Town, South Africa
- 13. Centre for Health Economics, Alcuin College, University of York, York, YO10 5DD, UK
- 14. Center of Pharmacoeconomics, University of Milan, Via Vanvitelli 32, 20129, Milan, Italy
- 15. CHARTA Foundation, c/o Department of Medical Pharmacology, University of Milan, Via Vanvitelli 32, 20129, Milan, Italy
- 16. Department for Health Economics and Health Care Management, School of Public Health, University of Bielefeld, P.O. Box 10 01 31, 33501, Bielefeld, Germany