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A Comparative Study on the Sensitive Detection of Hydroxyl Radical Using Thiol-capped CdTe and CdTe/ZnS Quantum Dots

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Abstract

Four types of water-soluble luminescent quantum dots (QDs) whose surface was functionlaized with thioglycolic acid (TGA), 3-mercaptopropionic acid (MPA), or glutathione (GSH), were investigated for the sensitive and selective detection of hydroxyl radical (●OH) in aqueous media. It was found that the type of capping agent and QD influenced the sensitivity of the probe. The order of sensitivity of the probe was: GSH-CdTe@ZnS > MPA-CdTe@ZnS > TGA-CdTe > MPA-CdTe QDs. Under the optimum conditions, a limit of detection as low as 8.5 × 10-8 M was obtained using GSH-CdTe@ZnS. The effects of foreign reactive oxygen species and the Fenton reactants and products as possible interferences on the proposed probe were negligible for CdTe@ZnS QDs. Besides, experimental results indicated that CdTe@ZnS QDs were more attractive for the selective recognition of ●OH than CdTe QDs. The mechanistic reaction pathway between the QDs and ●OH is proposed.

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Acknowledgements

This work was supported by the Department of Science and Technology (DST) and National Research Foundation (NRF), South Africa through DST/NRF South African Research Chairs Initiative for Professor of Medicinal Chemistry and Nanotechnology as well as Rhodes University and DST/Mintek Nanotechnology Innovation Centre (NIC) – Sensors, South Africa.

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  1. Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa

    Oluwasesan Adegoke & Tebello Nyokong

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  1. Oluwasesan Adegoke
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  2. Tebello Nyokong
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Correspondence to Tebello Nyokong.

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Adegoke, O., Nyokong, T. A Comparative Study on the Sensitive Detection of Hydroxyl Radical Using Thiol-capped CdTe and CdTe/ZnS Quantum Dots. J Fluoresc 22, 1513–1519 (2012). https://doi.org/10.1007/s10895-012-1089-2

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  • DOI: https://doi.org/10.1007/s10895-012-1089-2

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