Skip to main content

Advertisement

Log in

Psychological Treatment Improves Hemoglobin A1c Outcomes in Adolescents with Type 1 Diabetes Mellitus

  • Published:
Journal of Clinical Psychology in Medical Settings Aims and scope Submit manuscript

Abstract

Adolescents diagnosed with Type 1 Diabetes Mellitus often exhibit reduced adherence to their medical regimen and poor glycemic control. A retrospective study examined longitudinal hemoglobin A1c (HgbA1c) outcomes for adolescent patients referred to the psychology service embedded within an endocrinology clinic. Three patient groups were examined: (1) Treatment: 59 adolescents referred who engaged in psychotherapy; (2) No Treatment: 40 adolescents referred yet failed to initiate psychotherapy; (3) Control: 58 adolescents not referred for treatment and matched on demographics to the two treatment groups. Over 1 year, the Treatment group had a sustained decrease in HgbA1c while the No Treatment and Control groups had an overall increase in HgbA1c. At study end, the Treatment group had HgbA1c values that were not significantly different from patients who were not considered in need of psychological treatment (Control). Adolescents that utilized the pediatric psychology service saw decreased HgbA1c values over time.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Armstrong, F. D., Harris, L. L., Thompson, W., Semrad, J. L., Jensen, M. M., Lee, D. Y., et al. (1999). Integration of pediatric psychology with primary medical care for children infected with HIV. Journal of Pediatric Psychology, 24, 381–391.

    Article  PubMed  CAS  Google Scholar 

  • Bryden, K. S., Peveler, R. C., Stein, A., Neil, A., Mayou, R. A., & Dunger, D. B. (2001). Clinical and psychological course of diabetes from adolescence to young adulthood: A longitudinal cohort study. Diabetes Care, 24, 1536–1540.

    Article  PubMed  CAS  Google Scholar 

  • Bryden, K. S., Dunger, D. B., Mayou, R. A., Peveler, R. C., & Neil, H. A. (2003). Poor prognosis of young adults with type 1 diabetes: A longitudinal study. Diabetes Care, 26, 1052–1057.

    Article  PubMed  Google Scholar 

  • Carney, R. M., Schechter, K., & Davis, T. (1983). Improving adherence to blood glucose monitoring in insulin-dependent diabetic children. Behavior Therapy, 14, 247–254.

    Article  Google Scholar 

  • Ceriello, A., Ihnat, M. A., & Thorpe, J. E. (2009). The “metabolic memory”: Is more than just tight glucose control necessary to prevent diabetic complications? Journal of Clinical Endocrinology and Metabolism, 94, 410–415. doi:10.1210/jc.2008-1824.

    Article  PubMed  CAS  Google Scholar 

  • Cohen, M. S. (1999). Families coping with childhood chronic illness: A research review. Families, Systems and Health, 17(2), 149.

    Article  Google Scholar 

  • Daneman, D., Epstein, L. H., Siminerio, L. A., Beck, S., Farkas, G., Figueroa, J., et al. (1981). Effects of enhanced conventional therapy on metabolic control in children with insulin dependent diabetes mellitus. Diabetes Care, 5, 472–478.

    Article  Google Scholar 

  • Delamater, A. M. (2007). Psychological care of children and adolescents with diabetes. Pediatric Diabetes, 8, 340–348.

    Article  PubMed  Google Scholar 

  • Ellis, D. A., Naar-King, S., Frey, M., Templin, T., Rowland, M., & Greger, N. (2004). Use of multi-systemic therapy to improve regimen adherence among adolescents with type I diabetes in poor metabolic control: A pilot investigation. Journal of Clinical Psychology in Medical Settings, 11, 315–324.

    Article  Google Scholar 

  • Ellis, D. A., Naar-King, S., Frey, M., Templin, T., Rowland, M., & Cakan, N. (2005). Multisystemic treatment of poorly controlled type 1 diabetes: Effects on medical resource utilization. Journal of Pediatric Psychology, 30(8), 656–666.

    Article  PubMed  Google Scholar 

  • Epstein, L. H., Beck, S., Figueroa, J., Farkas, G., Kazdin, A. E., Daneman, D., et al. (1981). The effects of targeting improvement in urine glucose on metabolic control in children with insulin dependent diabetes mellitus. Journal of Applied Behavior Analysis, 14, 365–375.

    Article  PubMed  CAS  Google Scholar 

  • Fleming, E., Carter, B., & Gillibrand, W. (2002). The transition of adolescents with diabetes from the children’s health care service into the adult health care service: a review of the literature. Journal of Clinical Nursing, 11, 560–567.

    Article  PubMed  Google Scholar 

  • Grey, M. (2000). Interventions for children with diabetes and their families. Annual Review of Nursing Research, 18, 149–170.

    PubMed  CAS  Google Scholar 

  • Grey, M., Whittemore, R., Jaser, S., Ambrosino, J., Lindemann, E., Liberti, L., et al. (2009). Effects of coping skills training in school-age children with type 1 diabetes. Research in Nursing & Health, 2009, 405–418.

    Article  Google Scholar 

  • Hampson, S. E., Skinner, T. C., Hart, J., Storey, L., Gage, H., Foxcroft, D., et al. (2001). Effects of educational and psychosocial interventions for adolescents with diabetes mellitus: A systematic review. Health Technology Assessment, 5, 1–79.

    PubMed  CAS  Google Scholar 

  • Herzer, M., & Hood, K. K. (2010). Anxiety symptoms in adolescents with type 1 diabetes: association with blood glucose monitoring and glycemic control. Journal of Pediatric Psychology, 35, 415–425.

    Article  PubMed  Google Scholar 

  • Hilliard, M. E., Herzer, M., Dolan, L. M., & Hood, K. K. (2011). Psychological screening in adolescents with type 1 diabetes predicts outcomes one year later. Diabetes Research and Clinical Practice, 94(1), 39–44.

    Article  PubMed  Google Scholar 

  • Holmes, C. S., Chen, R., Streisand, R., Marschall, D. E., Souter, S., Swift, E. E., & Peterson, C. C. (2006). Predictors of youth diabetes care behaviors and metabolic control: A structural equation modeling approach. Journal of Pediatric Psychology, 31(8), 770–784.

    Article  PubMed  Google Scholar 

  • Hood, K. K. (2011). Reducing stress in adolescents with diabetes: what can be done? Diabetes Management, 1, 5–8.

    Article  Google Scholar 

  • Hood, K. K., Peterson, C. M., Rohan, J. M., & Drotar, D. (2009). Association between adherence and glycemic control in pediatric type 1 diabetes: A meta-analysis. Pediatrics, 124, e1171–e1179. doi:10.1542/peds.2009-0207.

    Article  PubMed  Google Scholar 

  • Hood, K. K., Rohan, J. M., Peterson, C. M., & Drotar, D. (2010). Interventions with adherence-promoting components in pediatric type 1 diabetes: Meta-analysis of their impact on glycemic control. Diabetes Care, 33, 1658–1664. doi:10.2337/dc09-2268.

    Article  PubMed  Google Scholar 

  • Hood, K. K., Rausch, J. R., & Dolan, L. M. (2011). Depressive symptoms predict change in glycemic control in adolescents with type 1 diabetes: Rates, magnitude, and moderators of change. Pediatric Diabetes, 12(8), 718–723.

    Google Scholar 

  • ISPAD. (2000). Consensus guidelines for the management of type 1 diabetes mellitus in children and adolescents. Available from http://www.diabetesguidelines.com/health/dkw/pro/guidelines/ispad/ispad/asp.

  • Jelalian, E., & Saelens, B. (1999). Empirically supported treatments in pediatric psychology: Pediatric obesity. Journal of Pediatric Psychology, 24, 223–248.

    Article  PubMed  CAS  Google Scholar 

  • Kahana, S., Drotar, D., & Frazier, T. (2008). Meta-analysis of psychological interventions to promote adherence to treatment in pediatric chronic health conditions. Journal of Pediatric Psychology, 33, 590–611. doi:10.1093/jpepsy/jsm128.

    Article  PubMed  Google Scholar 

  • Kilpatrick, E. S., Rigby, A. S., & Atkin, S. L. (2008). A1C variability and the risk of microvascular complications in type 1 diabetes. Diabetes Care, 31, 2198–2202. doi:10.2337/dc08-0864.

    Article  PubMed  Google Scholar 

  • La Greca, A. M., Auslander, W. F., Greco, P., Spetter, D., Fisher, E. B., & Santiago, J. V. (1995). I get by with a little help from my friends: Adolescent support for diabetes care. Journal of Pediatric Psychology, 20, 449–476.

    Article  PubMed  Google Scholar 

  • Lieberman, A., Adalist-Estrin, A., Erinle, O., & Sloan, N. (2006). On-site mental health care: a route to improving access to mental health services in an inner-city, adolescent medicine clinic. Child: Care, Health & Development, 32(4), 40–413.

    Google Scholar 

  • Lowe, K., & Lutzker, J. R. (1979). Increasing compliance to a medical regimen with a juvenile diabetic. Behavior Therapy, 10, 57–64.

    Article  Google Scholar 

  • McGrady, M. E., Laffel, L., Drotar, D., Repaske, D., & Hood, K. K. (2009). Depressive symptoms and glycemic control in adolescents with type 1 diabetes. Diabetes Care, 32, 804–806. doi:10.2337/dc08-2111.

    Article  PubMed  Google Scholar 

  • Miller-Johnson, S., Emery, R. E., Marvin, R. S., Clarke, W., Lovinger, R., & Martin, M. (1994). Parent-child relationships and the management of insulin-dependent diabetes mellitus. Journal of Consulting and Clinical Psychology, 62, 603–610.

    Article  PubMed  CAS  Google Scholar 

  • Satin, W., La Greca, A. M., Zigo, M. A., & Skyler, J. S. (1989). Diabetes in adolescence: Effects of multifamily group intervention and parent simulation of diabetes. Journal of Pediatric Psychology, 14(2), 259–275.

    Article  PubMed  CAS  Google Scholar 

  • Schafer, L. C., Glasgow, R. E., & McCaul, K. D. (1982). Increasing the adherence of diabetic adolescents. Journal of Behavioral Medicine, 5, 353–362.

    Article  PubMed  CAS  Google Scholar 

  • Siminerio, L. M. (2008). Approaches to help people with diabetes overcome barriers for improved health outcomes. Diabetes Education, 34, 18S–24S.

    Article  Google Scholar 

  • Snoek, F. J., & Skinner, T. C. (2002). Psychological counselling in problematic diabetes: Does it help? Diabetic Medicine, 19, 265–273.

    Article  PubMed  CAS  Google Scholar 

  • Thompson, R. D., Delaney, P., Flores, I., & Szigethy, E. (2011). Cognitive-behavioral therapy for children with comorbid physical illness. Child and Adolescent Psychiatric Clinics of North America, 20, 329–348. doi:10.1016/j.chc.2011.01.013.

    Article  PubMed  Google Scholar 

  • U.S. Department of Health and Human Services, C. f. D. C. a. P. (2011). National Diabetes Fact Sheet: National estimates and general information on diabetes and prediabetes in the United States. GA: Atlanta.

    Google Scholar 

  • Weibe, D. J., Berg, C. A., Korbel, C., Palmer, D. L., Beveridge, R. M., Upchurch, R., et al. (2005). Children’s appraisals of maternal involvement in coping with diabetes: Enhancing our understanding of adherence, metabolic control, and quality of life across adolescence. Journal of Pediatric Psychology, 30, 167–178.

    Article  Google Scholar 

  • Weissberg-Benchell, J., Glasgow, A. M., Tynan, W. D., Wirtz, P., Turek, J., & Ward, J. (1995). Adolescent diabetes management and mismanagement. Diabetes Care, 18, 77–82.

    Article  PubMed  CAS  Google Scholar 

  • Weissberg-Benchell, J., Wolpert, H., & Anderson, B. J. (2007). Transitioning from pediatric to adult care: A new approach to the post-adolescent young person with type 1 diabetes. Diabetes Care, 30, 2441–2446. doi:10.2337/dc07-1249.

    Article  PubMed  Google Scholar 

  • Wens, J., Vermeire, E., Hearnshaw, H., Lindenmeyer, A., Biot, Y., & Van Royen, P. (2008). Educational interventions aiming at improving adherence to treatment recommendations in type 2 diabetes: A sub-analysis of a systematic review of randomised controlled trials. Diabetes Research and Clinical Practice, 79(3), 377-388. doi:10.1016/j.diabres.2007.06.006.

    Google Scholar 

  • Wills, C. J., Scott, A., Swift, P. G., Davies, M. J., Mackie, A. D., & Mansell, P. (2003). Retrospective review of care and outcomes in young adults with type 1 diabetes. British Medical Journal, 327, 260–261. doi:10.1136/bmj.327.7409.260.

    Article  PubMed  CAS  Google Scholar 

  • Wysocki, T. (1993). Associations among teen-parent relationships, metabolic control and adjustment to diabetes in adolescents. Journal of Pediatric Psychology, 18, 443–454.

    Article  Google Scholar 

  • Wysocki, T. (2006). Behavioral assessment and intervention in pediatric diabetes. Behavior Modification, 30, 72–92. doi:10.1177/0145445505284275.

    Article  PubMed  Google Scholar 

  • Wysocki, T., Harris, M. A., Buckloh, L. M., Mertlich, D., Lochrie, A. S., Taylor, A., ... & White, N. H. (2006). Effects of behavioral family systems therapy for diabetes on adolescents’ family relationships, treatment adherence, and metabolic control. Journal of Pediatric Psychology, 31(9), 928–938.

  • Wysocki, T., Taylor, A., Hough, B. S., Linscheid, T. R., Yeates, K. O., & Naglieri, J. A. (1996). Deviation from developmentally appropriate self-care autonomy: Association with diabetes outcomes. Diabetes Care, 19, 119–125.

    Article  PubMed  CAS  Google Scholar 

  • Wysocki, T., Greco, P., Harris, M. A., Harvey, L. M., McDonell, K., Elder, C. L., et al. (1997). Social validity of support group and behavior therapy interventions for families of adolescents with insulin-dependent diabetes mellitus. Journal of Pediatric Psychology, 22, 635–650.

    Article  PubMed  CAS  Google Scholar 

  • Wysocki, T., Harris, M. A., Greco, P., Bubb, J., & White, N. H. (2001). Behavior therapy for families of adolescents with diabetes: Maintenance of treatment effects. Diabetes Care, 24, 441–446.

    Article  PubMed  CAS  Google Scholar 

  • Wysocki, T., Harris, M., Buckloh, L. M., Locrhie, A., Mertlich, D., Wilkinson, K., et al. (2005). Effects of behavioral family systems therapy on adolescents’ diabetes outcomes. Diabetes, 53, A19.

    Google Scholar 

  • Wysocki, T., Harris, M. A., Buckloh, L. M., Mertlich, D., Lochrie, A. S., Mauras, N., et al. (2007). Randomized trial of behavioral family systems therapy for diabetes: maintenance of effects on diabetes outcomes in adolescents. Diabetes Care, 30, 555–560.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This study was supported in part by a grant from the American Cancer Society to MK Bean. [PFT-08-144-01-CPPB], which had no involvement with the conduct of the research or preparation of the manuscript. We are grateful to the patients and families who participated in this study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Matthew J. Bitsko.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bitsko, M.J., Bean, M.K., Bart, S. et al. Psychological Treatment Improves Hemoglobin A1c Outcomes in Adolescents with Type 1 Diabetes Mellitus. J Clin Psychol Med Settings 20, 333–342 (2013). https://doi.org/10.1007/s10880-012-9350-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10880-012-9350-z

Keywords

Navigation