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A bioresorbable polylactide implant used in bone cyst filling

  • Biomaterials Synthesis and Characterization
  • Clinical Investigation
  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

The aims in treating patients diagnosed with critical-sized bone defects resulting from bone cysts are to replace the lost bone mass after its removal and to restore function. The standard treatment is autologous or allogeneic bone transplantation, notwithstanding the known consequences and risks due to possible bone infection, donor site morbidity, bleeding and nerve injury and possible undesirable immune reactions. Additionally, allogeneic grafts are inhomogeneous, with a mosaic of components with difficult-to-predict regenerative potential, because they consist of cancellous bone obtained from different bones from various cadavers. In the present study, a 22-year-old patient with a history of right humerus fracture due to bone cysts was diagnosed with recurrent cystic lesions based on X-ray results. The patient qualified for an experimental program, in which he was treated with the application of a bioresorbable polylactide hybrid sponge filled with autologous platelet-rich plasma. Computed tomography and magnetic resonance imaging performed 3, 6, and 36 months after surgery showed progressive ossification and bone formation inside the defect cavity in the humerus. Three years after treatment with the bone substitute, the patient is pain free, and the cystic lesions have not reoccurred.

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Acknowledgments

This study was supported by the kind cooperation of Bioimplant, Ltd., Poland.

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Authors and Affiliations

  1. Galen-Orthopaedics, Jerzego 6, 43-150, Bierun, Poland

    Krzysztof Ficek, Jolanta Filipek, Piotr Wojciechowski & Konrad Kopec

  2. Department of Physical Culture and Health Promotion, University of Szczecin, al. Piastow 40B, 70-453, Szczecin, Poland

    Krzysztof Ficek

  3. Academy of Physical Education, Mikolowska 72A, 40-065, Katowice, Poland

    Krzysztof Ficek

  4. Department of Orthopaedics and Traumatology, Medical University of Silesia, School of Medicine in Katowice, Ziolowa 45/47, 40-752, Katowice, Poland

    Piotr Wojciechowski & Konrad Kopec

  5. Department of Biomaterials, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Mickiewicza 30, 30-059, Krakow, Poland

    Stodolak-Zych Ewa & Stanislaw Blazewicz

Authors
  1. Krzysztof Ficek
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  2. Jolanta Filipek
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  5. Stodolak-Zych Ewa
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  6. Stanislaw Blazewicz
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Correspondence to Krzysztof Ficek.

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Ficek, K., Filipek, J., Wojciechowski, P. et al. A bioresorbable polylactide implant used in bone cyst filling. J Mater Sci: Mater Med 27, 33 (2016). https://doi.org/10.1007/s10856-015-5647-4

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  • DOI: https://doi.org/10.1007/s10856-015-5647-4

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