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TiNi shape memory alloy coated with tungsten: a novel approach for biomedical applications

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Abstract

This study explores the use of DC magnetron sputtering tungsten thin films for surface modification of TiNi shape memory alloy (SMA) targeting for biomedical applications. SEM, AFM and automatic contact angle meter instrument were used to determine the surface characteristics of the tungsten thin films. The hardness of the TiNi SMA with and without tungsten thin films was measured by nanoindentation tests. It is demonstrated that the tungsten thin films deposited at different magnetron sputtering conditions are characterized by a columnar microstructure and exhibit different surface morphology and roughness. The hardness of the TiNi SMA was improved significantly by tungsten thin films. The ion release, hemolysis rate, cell adhesion and cell proliferation have been investigated by inductively coupled plasma atomic emission spectrometry, CCK-8 assay and alkaline phosphatase activity test. The experimental findings indicate that TiNi SMA coated with tungsten thin film shows a substantial reduction in the release of nickel. Therefore, it has a better in vitro biocompatibility, in particular, reduced hemolysis rate, enhanced cell adhesion and differentiation due to the hydrophilic properties of the tungsten films.

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References

  1. El Feninat F, Laroche G, Fiset M, Mantovani D. Shape memory materials for biomedical applications. Adv Eng Mater. 2002;4:91–104.

    Article  Google Scholar 

  2. Chu CL, Chung CY, Lin PH, Wang SD. Fabrication of porous NiTi shape memory alloy for hard tissue implants by combustion synthesis. Mater Sci Eng A. 2004;366:114–9.

    Article  Google Scholar 

  3. Castleman LS, Motzkin SM, Alicandri FP, Bonawit VL, Johnson AA. Biocompatibility of nitinol alloy as an implant material. J Biomed Mater Res. 1976;10:695–731.

    Article  Google Scholar 

  4. Duerig T. Present and future applications of shape memory and superelastic materials. In:Materials research society symposium proceedings, Cambridge University Press, UK. 1995. p. 497.

  5. Shevchenko N, Pham MT, Maitz MF. Studies of surface modified NiTi alloy. Appl Surf Sci. 2004;235:126–31.

    Article  Google Scholar 

  6. Zhao H, Tian CC, Lin GQ, Ge ZD, Qi M, Yang DZ. Formation of Porous (Ca, P)-Doped TiO2/Dense Ti double coatings on NiTi alloy. In: Material science forum: Trans Tech Publications, Stafa-Zurich. 2011. p. 333–336.

  7. Köster R, Vieluf D, Kiehn M, Sommerauer M, Kähler J, Baldus S, et al. Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet. 2000;356:1895–7.

    Article  Google Scholar 

  8. Lincks J, Boyan B, Blanchard C, Lohmann C, Liu Y, Cochran D, et al. Response of MG63 osteoblast-like cells to titanium and titanium alloy is dependent on surface roughness and composition. Biomaterials. 1998;19:2219–32.

    Article  Google Scholar 

  9. Elias CN, Oshida Y, Lima JHC, Muller CA. Relationship between surface properties (roughness, wettability and morphology) of titanium and dental implant removal torque. J Mech Behav Biomed Mater. 2008;1:234–42.

    Article  Google Scholar 

  10. Lampin M, Warocquier-Clérout R, Legris C, Degrange M, Sigot-Luizard M. Correlation between substratum roughness and wettability, cell adhesion, and cell migration. J Biomed Mater Res. 1997;36:99–108.

    Article  Google Scholar 

  11. Choi J, Bogdanski D, Köller M, Esenwein SA, Müller D, Muhr G, et al. Calcium phosphate coating of nickel–titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets. Biomaterials. 2003;24:3689–96.

    Article  Google Scholar 

  12. Kobayashi S, Ohgoe Y, Ozeki K, Sato K, Sumiya T, Hirakuri K, et al. Diamond-like carbon coatings on orthodontic archwires. Diamond Relat Mater. 2005;14:1094–7.

    Article  Google Scholar 

  13. Chu C, Chung C, Zhou J, Pu Y, Lin P. Fabrication and characteristics of bioactive sodium titanate/titania graded film on NiTi shape memory alloy. J Biomed Mater Res Part A. 2005;75:595–602.

    Article  Google Scholar 

  14. Li Y, Wei SB, Cheng XQ, Zhang T, Cheng GA. Corrosion behavior and surface characterization of tantalum implanted TiNi alloy. Surf Coat Technol. 2008;202:3017–22.

    Article  Google Scholar 

  15. Jin S, Zhang Y, Wang Q, Zhang D, Zhang S. Influence of TiN coating on the biocompatibility of medical NiTi alloy. Colloids Surf B. 2013;101:343–9.

    Article  Google Scholar 

  16. Lee WC. Functional coatings on Ti-6Al-4 V and NiTi shape memory alloy for medical applications. Biomaterials. 2011;516:10–9.

    Google Scholar 

  17. Sun T, Lee WC, Wang M. A comparative study of apatite coating and apatite/collagen composite coating fabricated on NiTi shape memory alloy through electrochemical deposition. Mater Lett. 2011;65:2575–7.

    Article  Google Scholar 

  18. Peuster M, Fink C, von Schnakenburg C. Biocompatibility of corroding tungsten coils: in vitro assessment of degradation kinetics and cytotoxicity on human cells. Biomaterials. 2003;24:4057–61.

    Article  Google Scholar 

  19. Li HF, Zheng YF, Xu F, Jiang JZ. In vitro investigation of novel Ni free Zr-based bulk metallic glasses as potential biomaterials. Mater Lett. 2012;75:74–6.

    Article  Google Scholar 

  20. Li H, Wang Y, Zheng Y, Lin J. Osteoblast response on Ti—and Zr-based bulk metallic glass surfaces after sand blasting modification. J Biomed Mater Res B. 2012;100:1721–8.

    Article  Google Scholar 

  21. Turkin A, Pei Y, Shaha K, Chen C, Vainshtein D, De Hosson JTM. On the evolution of film roughness during magnetron sputtering deposition. J Appl Phys. 2010;108:094330–9.

    Article  Google Scholar 

  22. Schwartz Z, Lohmann C, Oefinger J, Bonewald L, Dean D, Boyan B. Implant surface characteristics modulate differentiation behavior of cells in the osteoblastic lineage. Adv Dent Res. 1999;13:38–48.

    Article  Google Scholar 

  23. Roach P, Eglin D, Rohde K, Perry CC. Modern biomaterials: a review—bulk properties and implications of surface modifications. J Mater Sci Mater Med. 2007;18:1263–77.

    Article  Google Scholar 

  24. Fu YQ, Wei J, Batchelor AW. Some considerations on the mitigation of fretting damage by the application of surface-modification technologies. J Mater Process Technol. 2000;99:231–45.

    Article  Google Scholar 

  25. Yang H, Pei Y, De Hosson JTM. Oxide-scale growth on Cr 2AlC ceramic and its consequence for self-healing. Scr Mater. 2013;69:203–6.

    Article  Google Scholar 

  26. ISO 10993-4. Biological evaluation of medical devices. Part 4: selection of tests for interactions with blood. Med Device Technol. 2001;12:32.

    Google Scholar 

  27. Lovmand J, Justesen J, Foss M, Lauridsen RH, Lovmand M, Modin C, et al. The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization. Biomaterials. 2009;30:2015–22.

    Article  Google Scholar 

  28. Bernard SA, Balla VK, Davies NM, Bose S, Bandyopadhyay A. Bone cell–materials interactions and Ni ion release of anodized equiatomic NiTi alloy. Acta Biomater. 2011;7:1902–12.

    Article  Google Scholar 

  29. Webb K, Hlady V, Tresco PA. Relative importance of surface wettability and charged functional groups on NIH 3T3 fibroblast attachment, spreading, and cytoskeletal organization. J Biomed Mater Res. 1998;41:422.

    Article  Google Scholar 

Download references

Acknowledgments

This work was supported by the National Basic Research Program of China (973 Program) (Grant Nos. 2012CB619102 and 2012CB619100), National Science Fund for Distinguished Young Scholars (Grant No. 51225101) and the China Exchange Programme of the Royal Netherlands Academy of Arts and Sciences (KNAW) (project “Surface modification of novel metallic biomaterials”).

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Authors and Affiliations

  1. State Key Laboratory for Turbulence and Complex System and Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing, 100871, China

    Huafang Li & Yufeng Zheng

  2. Department of Applied Physics, Materials Innovation Institute M2i and Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands

    Y. T. Pei & J. Th. M. De Hosson

  3. Department of Advanced Production Engineering, Institute for Technology and Management, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands

    Y. T. Pei

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  1. Huafang Li
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  2. Yufeng Zheng
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  3. Y. T. Pei
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  4. J. Th. M. De Hosson
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Correspondence to Yufeng Zheng or Y. T. Pei.

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Li, H., Zheng, Y., Pei, Y.T. et al. TiNi shape memory alloy coated with tungsten: a novel approach for biomedical applications. J Mater Sci: Mater Med 25, 1249–1255 (2014). https://doi.org/10.1007/s10856-014-5158-8

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  • DOI: https://doi.org/10.1007/s10856-014-5158-8

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