References
Esserman LJ, Alvarado MD, Howe RJ et al (2014) Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time? Breast Cancer Res Treat 144(2):371–378
Vaidya JS, Wenz F, Bulsara M et al (2014) Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial. Lancet 383(9917):603–613. doi:10.1016/S0140-6736(13)61950-9
Vaidya JS, Joseph DJ, Tobias JS et al (2010) Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial. Lancet 376(9735):91–102
Veronesi U, Orecchia R, Maisonneuve P et al (2013) Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): a randomised controlled equivalence trial. Lancet Oncol 14:1269–1277
Hughes KS, Schnaper LA, Bellon JR et al (2013) Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343. J Clin Oncol 31(19):2382–2387
Davies C, Pan H, Godwin J et al (2013) Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial. Lancet 381(9869):805–816
Leonardi MC, Maisonneuve P, Mastropasqua MG et al (2013) Accelerated partial breast irradiation with intraoperative electrons: using GEC-ESTRO recommendations as guidance for patient selection. Radiother Oncol 106(1):21–27
Smith GL, Xu Y, Buchholz TA et al (2012) Association between treatment with brachytherapy vs whole-breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancer. JAMA 307(17):1827–1837
Kaidar-Person O, Yarnold J, Offersen BV, Poortmans P (2014) Is current evidence about intraoperative partial breast irradiation sufficient for broad implementation in clinical practice? Eur J Surg Oncol 27. doi:10.1016/j.ejso.2014.03.014
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Additional information
This letter to the editor refers to the article available at doi:10.1007/s10549-014-2881-2 and a rebuttal letter to this letter to the editor is available at doi:10.1007/s10549-014-3036-1.
Rights and permissions
About this article
Cite this article
Kaidar-Person, O., Poortmans, P., Klimberg, S. et al. Haste makes waste: Are the data regarding TARGIT-A IORT ready for prime time?. Breast Cancer Res Treat 147, 221–222 (2014). https://doi.org/10.1007/s10549-014-3032-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10549-014-3032-5